Já, komið heilar og sæli, kæri hlustendur og verið hjartalega velkomnið í heilísu hlaðvarp Lukku og Jóhuna Viljáms.Lukka, við erum með alveg ótrúlega einstakann gest með okkur í dag, sem að á sér alveg einstakar vegferðog það er bara heiður að fá að tala einna við hana. Viðtalið við erum fyrirfram á ennsku, enda kemur hún frá bandarikinum og talar sjálf bara ennsku.Ég vildi bara byrja kannski aðeins svona á íslensku og hún var að tala á ráðstöfnu sem fór hérna fram á dögunum sem heitir Health for the Futuresem að snýst raunverulega um auki val og skada mingun. Við horfum ekki bara á þess að meðferðir hvað er leift og hvað er ekki leift,heldur hvernig getur við hlusta á sjúklingarna og það er daldur hennar vegur, akkur hún er í þessu.En svo saði við mig í dag, hún saði hvernig gætu?Það ætti ég ekki fara þessa leið og hort bara þegar ég vissi hún var að virka og hort á börnin sem ég var að þetta barnalagnir kvæljast.Emmitt og þú hróf sér henni fyrir hugur ekki og hún bent á að hún hefði ekkit vald, hún er yfir það að vera hugurökvegna þess að hún gæti ekki bara að horta börn þjást þegar hún vissi að það væri til eitthvað sem að hjálpa.Já.Skilna vel.Já.Og þannig ég ætla að bara að kynna, skipta hérna yfir í ennsku og hafa áganginu, inganginu um þannig.And Dr. Bonnie Goldstein is one of the most experienced physicians working in the field of medical cannabis today.But this is not where her medical career began.She trained as a pediatrician at Children's Hospital in Los Angeles where she also served as chief resident and later worked in pediatric emergency medicine.Her journey into cannabinoid medicine began after seeing a seriously ill friend experience significant benefits from cannabis.And then what you do?And since 2008, Bonnie has worked with thousands of children and adults including patients with treatment-resistant epilepsy, autism, cancer, chronic pain and other complex conditions.She is the medical director of Cannacenters Wellness and Education.She is the founder of Goldstein Wellness and the author of two books on cannabis, Cannabis as Medicine and Cannabis Revealed.And she is also in the movie Weed Them, I think the name, but she will maybe correct me, Dr. Bonnie Goldstein.So, such a pleasure and honor to have you here with us today.Thank you for having me.And it's Weed the People.Yeah, it's Weed Them, yeah, Weed the People, yeah.So, I'm just gonna...Yeah, I'm gonna put the mic a little bit more close to you.So, I mean, you have now at least 18 years, is that right, in treating your patients with cannabis.But I think, I mean, for those that have never heard of you before and it's really interesting, I mean, how your story evolved.How did it start?A little bit came in, you saw a close friend.Right.Well, I was at a point in my life, I had been a doctor.At that point for probably 15 years, I did critical care transport medicine, picking up very ill children and moving them to a tertiary hospital for, you know, ongoing care.And after that, I worked many years in pediatric emergency medicine of a little over a decade.But the medical system was becoming more difficult.I was finding it very difficult to take good care of my patients.Because of the...The system.Meaning, you know, spending a lot of time on the phone, begging them to transfer the little baby to the appropriate facility for ongoing care.Just a lot of difficulty within the medical system in the United States, which I think many people have heard of, you know.And so, and at the time, I had a friend who was fighting cancer and she asked me about medical cannabis.This was in around 2007.In 1996, California was the first state to......pass a medical cannabis law.It was voted on by the people, not passed by the legislature.And I will tell you, nobody wanted that law except the people.The government didn't want it.Law enforcement didn't want it.The medical community didn't want it.It was really an uphill battle, but people voted for it.And I believe that stemmed out of the HIV AIDS epidemic.But my friend was ill.She asked me about cannabis and I said, oh, gosh, I remember from college.But I didn't know what it was.But I don't really know the science.Let me look into it.And little did I know that inside the scientific literature, there was the description of this system that lives within us that I did not learn about in medical school.Which is?The endocannabinoid system.It was discovered really in 1988 through about 1992.It was a number of research and kind of the evolution of that science.I was in medical school, 1986 to 1990.So I didn't learn about it.They were just discovering it.But there was now like, you know, a decade and a half of research by 2008, almost 20 years actually.And I started reading.I said, how am I a doctor?And I don't know about this.It's a basic system for survival.It gives you resilience.It gives you homeostasis.It is a crucial.It is a crucial system to your well-being.The system is in all of us.Any animal with a spine has it.And even very simple creatures in the ocean like sea squirts, they have portions of it.And this system evolved to help us balance in response to stressors like inflammation.Traumatic insult, an injury, to infection.The system kicks in and it tells your cells send a balanced message.It's good to send a message to your body, something's wrong.But you're not supposed to live in that space of something's wrong.Your endocannabinoid system kicks in and balances you.And believe it or not, part of that system is an inner, multiple inner.Cannabis-like compounds.So people who look at the plant and see THC and CBD,we actually make compounds that look just like that plant.Inside our own bodies.Inside our own brains and bodies.And those compounds, we release them on demand.They're made from healthy fat.We release them on demand when we need themto help shift the messages that the cells are sending.Like imagine your brain is sending the message of panic, panic, panic.Your brain is...It's supposed to kick in this inner cannabis to lower that panic,to get you back into what we call homeostasis.So it is a homeostatic regulator of our physiology.We cannot ignore it any longer.So you said they discovered this quite recently.And that could be the reason that it was not included in your studies.But is it now?Do you know?In the medical study?That's a great question.The United States...They say about 14% of medical schoolsinclude some minor education on the endocannabinoid system.So it is still being ignored.One of the things that's very...Well, let me state two things.One is in medical school, when I went to school,and I think it's the same,you learn about the neurology,you learn about the lungs,you learn of cardiovascular,you learn about like the lymphatic system.The endocannabinoid system,it's everywhere.It's not just in this or in that system.It's all connected.Could you say that, I mean,every cell almost has a receptor for this?Almost every cell.And the area of your brain,that could stop you from breathing,that has opioid receptors.So when people overdo opioids,you could shut down your breathing.We do not have cannabinoid receptors in that part of the brain.So there has been no...No fatal overdose of cannabis.However, you can make yourself feel terribleif you overdose and you can panic.It does...What's funny is it can give you the opposite of the benefit.So whereas a lot of people say it lowers anxiety,if you take too much, it triggers anxiety.And you could even become paranoid and have some issues.But of course, the key is if you're using it as medicine,there's no reason to take too much.But you started to learn about this system,and finding out, you know,all the good things about what it can,you know, how it could help your patients.So you started to use it inside your work.I mean, at this time, you were working at a patriotic department.I mean, you were handling with children.And how was that?Well, I...That...So that was separate.I left that work.Yeah.And took some time off from my own kind of sanity.And it was during that time,that my friend asked me about it.All right.And I feel like the universe was telling me something.It's time to change your focus.And I've always thought more naturally, I think, than most.And I've always been open to alternatives.When you take care of sick children,you must be open to alternatives.Because we don't have the solution to every problem.And you were saying to me today,how can people not want this just because they don't understand?And just tolerance.I think then, like you were saying,children that are really sickand that could get help from this,but not using it.That's right.And because there's fear.You know, one of the things I always say about cannabis,it's like a bad boyfriend.It has a lot of baggage.It comes with a lot of stigma and propaganda against it.That is very recent when you look at the history of cannabis in general.There's findings from thousands of years agothat cannabis was present during childbirth,when women gave birth.There's multiple reports in the historical and scientific literatureof cannabis being used as medicine for all kinds of things.Migraine, headaches, menopause, childbirth,as a poultice for arthritic joints.So we shouldn't ignore our history.Our ancestors used plants.They went outside and they found the medicine in their gardens.And in the woods, in the forest.And in the 1930s and 1940s,there was a concerted effort by people who had financial gainto take away cannabis.So cannabis became illegal around,in the United States around 1941,in terms of whether,doctors used to prescribe it.There are old apothecary bottles of cannabis sativa,and it even says for health and for wellness.And for headache, or whatever.And then we started to move into the pharmaceutical model.There were some other,I'm not going to go through the whole history.People can read about it.There's some wonderful stuff online about the history.But basically it was phased out.And then they used racism.And who was behind that?Well, people who had other,they didn't, they wanted you to use plastic.They wanted you, they wanted to get rid of the hemp plant.I mean the hemp plant is an incredibly useful plant.It can be used as fuel, food, materials, medicine,I mean, incredible.And they decided to make hemp illegal.In the United States in 1970,is when it really sealed the deal.They made it highly illegal,as part of what we call the Controlled Substance Act.And it was put in a Schedule 1.Schedule 1 is no medicinal value,high addictive potential,and lack of safety.And I will tell you,the cannabis doesn't fit any of those.But that's where it has left its mark.It has lived.And only until April of this year,when our current Federal Administrationdecided to move it from Schedule 1 to Schedule 3for medical purposes.But it's all now caught up in the courts.So still in the United States,very difficult.And one thing I'll share with you is thatfor most physicians especially,we work very hard to get,we go to school,we get in debt to go to school.We have licenses that we want to protect.If you said to me,Bonnie, I want you to prescribe a Schedule 1 drug,I would look at you and say,I'm not going to risk my license.But where I live in California,yes, we were in conflict with the Federal Government,but there was a,physicians under California law,when that law passed in 1996,it took some time,but by the time I got to it in 2008,when I first wrote my very first letterto approve a patient,it was kind of,okay, it's 12 years,the sky hasn't fallen,people are doing better.There's some cannabis communitythat patients could like look intoand try to find a doctor and find medicine.And I will tell you that after the first three months,and I will tell you the first day of that job,I was terrified because I didn't know very much,right?I knew the science part,but I didn't know the clinical part yet.But as a pediatrician,if you're a savvy pediatrician,you learn,because children can't always tell you what's wrong with them.So you learn to work within that model.After the first three months,I was hooked on this,meaning the patients were coming in telling me the same thing.I'm sleeping.I got off my sleeping pills.I got off my opioids.I mean,patient after patient after patient.And I thought,I know they're not meeting in the parking lot and saying,let's just tell her the same thing.This was their experience,their genuine,valid experience.And what I found was a wonderful connection with these patientsbecause they felt like they could be honest with meand share with me what this plant was doing for them.And it's not just the plant.They were also inviting other,other healthful things into their lives,away from the pills,right?And away from the,oh,we don't have anything to help you kind of mentality.And especially in women,oh,it's all in your head,right?And so I used to say,well,of course it's in my head.It's my endokannabinoid system.It's all over my brain.So of course it's in my head.But what we notice is what I've even had hired some doctors to work for mewho had the same epiphany after a few months of talking to patients.Bonnie,they all say the same thing.They're saying they can get off their pain pills or lower them,that they're a better worker.They're a better spouse.They're a better parent.And when you hear it,I,I almost get chills when I think about it becausethey're now in California in 2018,we passed a legal for anybody over 21.No one needs me anymore to go access medical cannabis.They can just go to the shop and buy it.Okay.If you're over 21 for the children,you still need to see a doctor and get approval.But for all,but I still am very busy.Why am I busy?Because people don't want to go.They don't want to go to a shop and just pick up over the counter.They want help to get off the pills.They want help.Which kind of cannabis should I use?So they want help,advice and supervision.And remember too,with cannabis,because it treats,it,it goes everywhere,right?We have an endokannabinoid system everywhere.We don't treat a diagnosis.If you think about the medical community,oh,you have migraine.This is what you take,right?If you have endometriosis,this is what we give you.Nothing cure,nothing,no curative,but we have all these pills for you,right?With cannabis,what I say to the patient is,okay,you have migraine,but tell me what bothers you most.Is it that you can't sleep at night?Is it that you can't go to work the next day?Is it,because if it was just one size fits all,everybody use THC and go about their business,but do we want people taking THC in the morning and driving to work,driving their children to school?Do we want them,then they go to work and they can't focus,right?We have to use all parts of this plant.And so remember the plant,which now has been vilified for so many years for one of its compounds.It has over five,six,700 compounds,some of which we haven't even really identified and understand what they do.But the point is,is that,and I'm going to quote one of my,my,um,uh,who I look up to.This is Dr.Rafael Mishulam,who was the doctor in Israel who discovered,he was a PhD in Israel researcher.He discovered THC and named it,right?But one of his very famous quotes is,this is a treasure trove of plant compounds.So it's not just this group of compounds called cannabinoids.And that's why the system is called the endo cannabinoid system.Endo for within,right?What you produce.Right.The plant produces phyto cannabinoids,plant cannabinoids,and those are biologically active in our body.And if you understand what their targets are,remember every medicine has a target in your body.So if you take a drug to block your dopamine receptor,right?They build that drug because they know what the receptor looks like.They build the drug to go and block that receptor.Well,these plant compounds interact with many receptors,enzymes,transporter molecules,all kinds of things in our body.And what's fascinating about it is,why shouldn't we look at those compounds the same way we look atother medicines that we take?To me it's another form of medicine.It just comes from the plant rather than from a laboratory.But it's already been 20 yearssince you could prescribe it in your country.30 years in California.30 years.30 years.1996.That's right.Yes.So it's 30 years.30 years in California.Even more time then.But why is there still stigma?I mean,there is,right?I told you,a bad boyfriend,lots of baggage,a lot of stigma.How do other doctors look at what you're doing?It's a very good question.Many of them are kind of curious,but within the way that they work,let's say they work for a big health maintenance organization,or they work for a hospital,all of that still looks down on this.And everybody keeps saying,we need more research,we need more this.But yet,as a schedule,and this is the real problem,as a schedule one drug,in our country,a schedule one drug,you cannot study the benefits.You can only study the detriment.So how am I going to do research to prove to you that it worksif I can only look at the bad?Explain what that is.I mean,why are the rules like that?And schedule one drugs,what does that mean?Because money talks,and no pharmaceutical company who can't patent and own thiswants you to have a natural plant.They don't want you growing it in your backyard.They don't want you going to a shop and buying it.They want you to buy pills.I mean,what is the other,give me another explanation.Because when you look at the science,and this is what I'm going to say,and I'll die on this hill,the science is irrefutable.You have an endokannabinoid system.And if you have a medical issue that we can target there,okay,with these compounds,it is no different than writing a prescription for a drugthat happens to be approved by the FDA.Because some drugs,for instance,some medications are approved with a study that showed benefits,but the studies that showed the detriment were not presented.So,they were not presented when they went to the FDA.That's true.Yeah.And so,they created this barrierthat I can't study it for its benefits.So,but I have to find out what the benefits are in order for it to move along.So,it's a,you know,they call it a catch 22.There's no winning.But each state in the United States has,has their,now we have something like,oh,I can't even tell you the number anymore.Like,it's a medical program.At least it might even be in the 40s now.I think there's only three states that absolutely denyand they're going to have a problembecause the federal government's saying now schedule three.Schedule three in the United States is a prescription.A doctor can write a prescription.But it's not in the,I mean,the doctors don't have to learn.It needs to be in the curriculum.It needs to be in the curriculum from when doctors are,when they're in medical school.There needs to be educationacross the board of,of the population,of all people.Like we have to start changing the stigma.They,they did a very good job with the propaganda.My father,who I lost last year,95 years old,was born in 1930and cannabis became illegal in,I think it was 1941.And so to him it was highly,you know,highly,highly illegal.And he,he just,he was,my,my father was a,a,I wouldn't say a rebel,but he like grew up on,you know,on the streets kind of kid,you know.He made something of himself,had a nice familyand was a wonderful father and grandfather.But,you know,he wouldn't touch it.I started him on it when he was 85,85 years oldwith beautiful results.Until the day he died,he took cannabis.And do you know at end of lifewhen I took care of him,I think we gave himone or two doses of morphineand maybe one dose of a,of a benzodiazepine.He did not have to take any drugsbecause he took cannabisfor his quality of life issues.Pain,sleep,anxiety.Very beneficial in those areas.And again,I want to make sure it's very clear.We're not talking about recreational use,people who use it to get high.We live in countrieswhere people use alcoholto get,to get high.We could call it whatever you want.Wasted stone obliterated.There's all kinds of words.How many words do we have?There's no debate about alcoholbeing beneficial in any way.Right.That's right.No amount of alcohol is safe.Right.The studies.Right.And we allow it.How about tobacco?Exactly.Okay.Not on schedule one.It has no safety,no medicinal value.Yeah.And we allow opioids.And it's addictive.So don't talk to me about,like,so this was clearly not,not the point of it all,right?The point of it was to control peopleand they didn't want people,they didn't want the plantbecause of the usefulness of the plant.It interferes with profit.Sorry,that's just what it isand I'm just going to be blunt about it.Yeah.Because if you're in the businessof helping peopleand making people well,cannabis should be in your formulary.As an option.As you recommend.As an option.And a clinician such as myselfwho understands itcan tell you whether or not,if you came to me,my father has this condition,do you think cannabis might help?Well,it depends on whether or notwe think his endocannabinoid systemis not giving him enoughof that homeostatic regulation.Now,I just also want to share somethingreally importantbecause I don't knowif we're going to get to it.I take care of a lot of children with autism.We have done studies to measurethe endocannabinoid systemin children with autism.We've looked at itin other conditions as wellbut I'm going to use autismas an example.Children with autismhave been foundin two separate studies,one in Californiaat Stanford Universityand one at a university in Israelto have lower levelsof their inner cannabis.So the inner cannabis that we make,our body makes on responseto some imbalanceto try to get it into balance.What if you don't make enoughof your endocannabinoid?You live in an imbalanced state.What do we see in children,not all,and I'm just going to say,of course,not everybody with autismneeds to have cannabisbut for patients who have,or children,young adultswho have difficult challengeswith autism.So like what?Aggression towards others.It makes it difficultto go to school.Aggression towards themselves.I've seen kids give themselvesa concussionfrom hitting their headson the ground or on the wall.Right?No sleep at night.Do you know,I have families that come to mewho say that the parents,they take turns sleeping.Monday night,mom sleeps.Tuesday night,dad sleepsbecause the child's up all night.This is not conduciveto a good quality of lifeand will end upmaking the parents sick.Right?The whole family.Right?The family as a unit.So if we know that they're low,we would call thatan endocannabinoid deficiency.What do we dowith other deficiencies?If you have vitamin D deficiency,what do we do?We treat it.Give you more vitamin D.There you go.Yeah.If you have an insulin deficiency,you're called a diabetic.And we give you insulin.And we give you insulin.Why would we leave somebodywith low levels of endocannabinoidcausing,manifesting asdifficult challengeslike sleep and aggressionand all of thatand then give them antipsychotics?But how do you measure it?So in,it's a great question.Right now,we're just movinginto the spacewhere maybeyou could get a blood test.But the problem is,is thatwe make our endocannabinoidswhen we need themand then our body recyclesthe materials.So if I were to measure,so in children with autism,they did blood.They measured blood.So what's the,what markers did they measure?They tried,they measured anandamidebut that is not a routine testthat people can get right now.However,and I'm going to present this tomorrowat the health,Health for the Future,Health for the Future conference.I'm going to present a little bitof my research that I've done.I worked with a companywhere we collected salivafrom 15 children with autismbefore,and these were all childrenwho had been maintainedon a medical cannabis programat least for a minimum one year.Many had been on for 10 years,but they had to be onat least one yearon a stable regimen of cannabis.So we collected salivain the morning.The parents did some behavioral surveysvalidated that we usein the clinicto assess behaviorand then the parents gave themtheir medical cannabisand then we collected their salivaand did the behavior surveystwo hours later.So we were able to measureand saliva is like a mirrorof what happenswhen a child has autism.It's like a mirrorof what happenswhen a child has autism.It's like a mirrorof what happenswhen a child has autism.It's like a mirrorof what happenswhen a child has autism.So saliva is like a mirrorinto the,it's as good as the blood.It's a mirrorinto the body's chemistryand what we foundis that with manyof the different biomarkers,these are just compoundsthat like,you know,if I did blood test,let's say,and I'm just going to give youa quick example,if I were to draw bloodfor cholesteroland your cholesterol is 300,the doctor gives youa cholesterol medicineand then you check itand it comes down to 150.Oh, good response.You're right in the goal.Perfect.Stay on your medicine.So that's howwhat we were kind of looking at,right,but not cholesterolbut all these other compoundsthat reflect pain,the endocannabinoid system,aggression,neuronal function,a whole slew of inflammation,bioenergetics,metabolism,all kinds of thingslike we testedfor 454 different biomarkersand what we foundis 65 cannabis responsive,meaning they changedin response to the treatmentand what was fascinatingand we were the first groupto show thiswhich is very exciting to meis that if the childhad a very high biomarker,a cannabis responsive biomarkerbefore their medical cannabis,it shifted towards,and I hate to use the word normal,but the normal range,like where you might call cholesterol,oh, it's in the normal range now,right,oh, you're a good responderto the medicine.What we found was thatthe kids that had very high levelsafter their cannabis,the biomarker moved towardsthe biomarkersthat were establishedby healthy childrenwho didn't have autism.If the biomarker was very lowor nonexistent,we could then measure it close,it moved up.So again,that homeostasis,meaning the biomarkerwas very high,it shifted towards normal,if it was very lowor nonexistent,it shifted up,create,it balanced,it showed a homeostatic effect.Now it's only 15 children,but the fascinating part of itwas that what the parentswere reporting to us,how they see their benefit,correlated with the shiftsin the physiology.So we were able to measurethe response.It wasn't just the parentssaying my child is better.Now I believe my parentswhen they come to me and say,my child's not doing well,because they will tell me,we need to shift something.It might be the dosing,it might be the formulation,it might be,it's just the wrong matchfor that child's physiology.But what we showed was thatwhat the parents were reportingwas measurableand correlated with what they saw.I think this is so interestingbecause,I mean,first I want to ask you,I mean,what are those children,what medicine do those children getif not cannabinoids or cannabis?Because I know that,I mean,here they're not given cannabis.So if they are dealingwith those symptomsthat you are prescribing,like bad sleep, aggressiveness,and...Self-injury.Self-injury,all of those things.I mean...Even non-verbal,some of my patientshave started speaking.Yes, I mean,I think this is so...And I don't make promises,we just say we're going to see.No, because they are toldthat this is not,I mean,curable.I mean,they're trying maybesome behavioral...Intervention, sure.Interventions,but not those biological interventions.Not that I know of.Right.So, I mean,what are they given then?Well,in the United...Right,in the United States,we have two antipsychotic medicationsthat are approved for the useand then we havewhat we call off-label,so sometimes they'll use antidepressant,anti-anxieties medications.Listen,when a parent comes to meand says,my child started antipsychoticthree months agoand has gained 40 poundsand nothing has changedin the aggression,now they have an 11-year-oldthat was 80 poundsand now is 100 poundsand 120 pounds in aggressive.They didn't make it better.And when you say antipsychotics,what kind of,I mean,are there SSRIs,like...No,they're actual,they're medicationscalled antipsychotics,yeah.And what is the...They,they work by regulating dopaminein the brainfor the most part.So,they're giving them...So,they're giving them,yeah,they're psychiatric medications.Yeah,I mean,they're...Yeah,and there's some evidence...There's some evidencefor schizophrenia.Yeah.But then it was approvedand it's approved for,and the way,listen to the wording,for the irritabilityassociated with autism.So,to me,now,for some people,if it's working,hey,I'll never take awaya medicine that's working.If a mother says to meor a father says to meit's working,I'll mess with it.They,that's their,they,I see a child in a window,right,when I see them.But there's huge side effectswith autism.Weight gain,I mean,all kinds of problems.And even the doctorswho specialize in thatsay they don't likegiving those medicines,but they feel...Even Parkinson's,like,symptoms.Oh yeah,irreversible tremor,right,exactly.And,and,again,to me,I have an oath,I took an oath,do no harm.Do I want,why would I trythe more toxic medicinefirstbefore I would trya natural medicine?I mean,well,you don't have any proofand whatnot,right?Now,there is a body of knowledgesince 2019,a body of dataon autism.There's clinical trials.It can actually benefitwhat we callthe core symptomsof autism.There are no medicationsfor the coresymptoms,which arethe repetitivebehaviorsand alsothe socialand the communicationissues.Those are our core symptoms.I have childrenthat begin speaking.I,even if it's notevidence,even if it's nota double blind trial.There you go.You know,that's evidence.There you go.And when a parent says to me,Anecdotal evidenceis also evidence.Right.When I have a parent who says,so parents will say,should we tell the school?I say,don't tell the school.You know why?Not because it's a secret.See if they notice anything.If you tell themyou planted a seedthat's either,and whether,how they feelabout cannabisand they say,oh,he's more,unbiased feedback.Parent says to me,the teachercame out to the carand rapped on the windowat pickup timeand said,what are you giving him?He's different.I had the headof a schoolspecifically for childrenwith autismcall me and say,the childwho we findthe most difficultin this schoolis now the biggest pleasureto deal with.I can't make that up.That's a parentreaching out to mesaying,look what this medicine did.And key here,key,the childrenare not impairedor intoxicatedin any way.I don't allowmy patientsto be impaired.Now if an adultat nighttimewants to be impairedand get a little highbefore they wantto go to bed,knock yourself out.But childrento go to school,no,they can't go to schoolglossy eyedand out of it.And believe me,parents knowthey'll call me.He's got glossy eyes.He's eating everythingin the kitchen.Okay,we gotta changethe regimen.I need to ask youbecause I mean nowpeople are listening here,I mean they,it's illegal,but it'sit's illegal nowto sellCPT oils.And that is to sayFor external use,like creams orLike creams, right.But they sell oiland they are just likewhat you sayin Iceland we say,I mean they are just lookingthrough their fingers.They know of coursepeople are taking it inside,but they say,okay,we allow this justRight.for skin use.But of course peopleare using this.I mean and this is,this is a,I mean we interviewed him.An extraordinary storyof a father and motherof a reallya daughter that hasone of the most difficult nerveNeurologicalNeurologicaldiseasein the world.And so they,they foundreally ridiculousto leave for herin cannabis.So that he,he needed to becomea criminalto import thisto begin with.Can you imagineto make,to save your child's lifeor to give your childa quality of lifethat you would give to,to a dying animalyou would treat betterthan we treatsome of these children.And it's,it's,and really what it isis,you know,it's the lackof compassionand being open.I'm sorry to saysome of my colleagues.Now,here and there,of course,there are doctorslike,so for instance,I know a handfulof neurologists now,pediatric neurologistswho have,who have adaptedthe ideathat CBDcan certainly be usedin patientsto help with autismor epilepsyor some otherchronic condition.We,the ideaof do no harmgets lostbecause people,there's so muchbrainwashingabout CBDand again,going backto the baggagejust to get you stoned.We understandwhen peopleare abusing heroinor if they taketheir opioid prescriptionresponsibly,right?We know the difference,yeah?Right?So someone who getsa prescriptionfor pain medicineand follows the instructionsand is using itand is not overdoing,they're not tryingto buy it on the street,whatever.And then we havesome unfortunate peoplewho fall into addiction,right?We have to separatein our brainthe medical usefrom the non-medical use.Now,I'll tell youmany, many years ago,one of the bravestphysicians everwas a doctorwho we callDr. Todd,Dr. Todd McAreain Californiawho was one of the first doctorsin 1996to recommend cannabisand he always said,any useis medicinal use.What he's sayingis when people use it,it makes them feel betterfor whatever reason.Maybe they're not diagnosedwith panic attacksbut they have them.Maybe they're not diagnosedwith insomniabut they find themselvesup all night.You know,when I meet with peoplein my office,sometimes young menwill come inand this is going backnow many years,they will come inand just say,you know,I never slept as a child.I would lay in my roomand I would finally fall asleepat three o'clockand then my momwould wake me upin the morningto go to schooland I couldn't functionat school.So then they label the childa learning disabilityor ADHDand then they put themon medicineand it's this cascade,right?But what they're explainingto me isthey didn't sleep at night.They don't sleep at night.There's something wrongwith your endocannabinoid systembecause it's crucialto you being balancedand getting rest.So what you learnin this practicewas I learnedto ask the detailsof the patientahead of time.Tell me aboutyour family history.Are there migraines,irritable bowel syndrome,autism,fibromyalgia,all of thesehave been associatedwith endocannabinoid systemdysfunctionin the family.I think there's a lotof researchin the scientific literature.I could go on for daysso when people tell methere's not enough research,no.I'm having troublekeeping up with it.So there's a lot of researchbut point being isthat if you identifysomebody with this problem,if your governmentmakes everything illegal,how then do youtreat your patient?I was lucky in Californiabecause we had a lawthat allowed meto treat the patientsand now we havea lot of statesthat do have those lawsbut the point isis that if the physiciansdon't know aboutthe endocannabinoid systemand you don't knowabout the plant,you're missing allthe informationto be able to helpyour patients.But why is it,I mean,would you sayin all sickness,the endo,what do you call that?Endocannabinoid systemor the ECS.Yeah, the ECS,the endo.Cannabinoid.Cannabinoid,endo cannabinoid.Got it.You just practice it,you'll get it.I will practice it,yeah, okay.But would you sayand if you arein any waynot in homeostasis,would you sayin all of those casesthis system is notas it should be?I would agree with thatand we knowthat chronic stress,chronic sleep deprivation,a poor diet,poor not exercising,not moving your body,an unhealthy microbiomein your gut,all of this is partof your endocannabinoid systemnot functioning well.So you can be bornwith an endocannabinoid system issueand when I say thatit's because yourreceptors,your inner cannabis compounds,the enzymes,they're all part of your genetics.So your genes dictateyour receptor statusand your endocannabinoid functionso we have,it's built into your geneticsand then if you add,let's say illnessor chronic stress on top,you can end upwith a endocannabinoid systemunderlying issuebut also,you know,I had many women come to mein the first yearsthat I was doing thiswho would sayafter childbirth,you know,I never recovered.It was a major stressor.Their endocannabinoid systemgot behind,right?It couldn't keep upwith the homeostatic pressurelet's say,right?They got out of balance.Then they have a newborn baby.They're not,we all knowif you've had babiesfor how many monthsand years,sometimes,especially if you havemore than one,so you can also havewhat we callan acquired issue,right?And then the chronic stress,the chronic sleep deprivation,the chronic,and I'm going to talkabout this tomorrowin my talk,the nature of chronic illnessis that it issomewhat refractory,that the current medical systemdoes not have a curefor chronic type illnesses,right?We live with fibromyalgia.We live with mygosis.We live with migraines.We live with irritablebowel syndrome.We live with inflammation.We live with the,you know,dementia,all of these conditionsand primarily what I seein my practiceis people who havewhat you might calla refractory condition,i.e.I can't just go,like if I havea gallbladder problem,they can take my gallbladder outand then I'm fine,right?I could go on my lifeand live the rest of my lifetotally finebut when you haveone of these other conditionsthat I mentioned,you need to finda way to manage it.The problem is,is like,and I'll share with you,I had a 27-year-oldcome into my practice.She had a bag fullof pill bottles,a bag full,pain medicine,sleep medicine,anxiety medicine,multiple psychiatric medicationsand she held it upand she's 27 years old.She said,I have been on thisfor seven years.So since she was 20 years oldwhen her anxiety startedand I think it waslike maybe her parent,one of her parentspassed away.It was very,you know,it's tragicand difficultbut she just keptgetting handed pillsand she showed me the bagand she said,I cannot live like this.I can't even think.Not the root cause.Not the root cause,exactly.And she said,and I'm going to be honestwith you doctor,I tried cannabis.I said,I'm glad you're honest with mebecause I can't help youif you're not honest with me.She said,and I will never forget this,I can still see hersitting across from me,this beautiful young woman.She said,I can't even stop shop for me.It treats everything for me.Now,not everybody gets that luckythat you're that greatof a responderbut she said,I sleep at night.My panic and anxietyis under control.My pain is down.She's off all of them.She stopped allof those medications.And is that whatyou typically see?I mean,do you see?It is typically what I see.Do you know,I have a pediatric patientin my,I have some other researchbeing published nowabout 600 patientswith three otherof my colleagues.75 years of cannabismedicine experienceamongst the four of us.Over,we all have thousandsof patientsbut 600 respondedto the survey,completed the survey.And one of the patientson that,in that 600,I'm proud to sayone of my pediatric patientsgot off of 14different medications.A chronically ill childwith cerebral palsyand epilepsyand some other stuff.14 medicines.This is,this is amazing.And just,yes,sorry.No,I just wanted toask herif she,because we all knowabout this bigopioid epidemicand,and how,you know,terribleit can be.Do you regularlysee peoplereduce their opioidusewhen they goon cannabis,medical cannabis?Yes,we do see that.In our reportthat's gonna be publishedin the next monthor two,maybe,three monthsbefore you canturn it in.We had a 63%of peoplereportedreducingor eliminatingmedicationsfor pain,seizure,sleep,psychiatricand so on.While improvingquality of lifeat the same time.There you go.We had a 1%side effect,a serious side effect rate.That meansout of 600 peoplewe saw seriousside effectsin six.Now,one was a childwith a seizure.It's medicationwas not relatedto the cannabis.One person felland wasn't sureif it wasfrom the cannabis.Now one patient,she was takingfive milligram THCfor sleep at night.She went backto the storeto her dispensaryto buy itand they had changedthe formulationto 10 milligram.So shetook a double doseand she felland she did hurt herself.She got dizzywhen she stood up.That isunfortunatelythe same thingthat can happenwith any medicineso cannabis shouldn'tand I'm findingthat theythe medical communitywants to hold cannabisto this high standardthat you can haveno side effects.You can have noit's medicine.It's not going to workfor the samein everybodyand of coursebut if you learnabout itit'sI'm going to tell youmy husband jokes aroundthat if you unzip methere's a chicken inside.I'm afraid of everything.Okay,I worked in the emergency room.I am afraidhe calls me a mommyin a chicken suita chicka chicken in a mommy suit.That's right.I'mI'mand people call mea pioneerand I'm braveand so on.I'm just neurotic.I make sureI rememberdo no harm.Make sure you lookat what medicationsthat people are takingbecause there arethere can bedrug drug interactionswith cannabisso you shouldn'ttake it unlessif you're on medicationunless you talkto somebody who knowsa pharmacistwho's awho's familiarwith cannabis medicineor at least Google itgo online and lookbutespeciallywith peopleyou just want to make sureyou're covering all basesand you'reyou justyouwe should just treat itlike every other medicine.I don't know how else to say itbut it's saferand it's more flexiblebut do you also seesome positive side effectslike I'veoh absolutelywe seemaybemaybe people lovingtheir parents morerightbeing more open-heartedso this is what I'llI'll share with youI'm going to talk about it tomorrowa little bitbut I'll share with youwhat I've foundand what I've foundis thatif you come infor one specific thingand then like this womanwho came to mewith the bag of pillsthey findit doesn't just treatthat one thingthat there'sthis is betterthis is betterthis is betterthis is betterand sothere's a report out of Israelthat looked at children usingCBD dominantcannabis oilfor epilepsyand whatin thein the abstractwhat they wrotewaspositive benefitsseizure reductionlike whatmore alerthow about eye contactI have aa patientand Imy mother is very happywhen I talk about hershe was one of the first patientsshe waswe were just lookingher charts very thickin my filebecause she's been my patientsince she's 10and she'sgoing to be 22she was bornwith a genetic conditionit's a glycosylation issueeach one of her cellscan't go throughthis certain processcalled glycosylationanywayshe came to meat age ninehaving hundreds of seizures a dayon the EEGso you knowthey put those little thingson her headshe's just having seizuresseizuresseizuresat the age of nineshe was in a strollerthe sameI would saybrain developmentas a two month oldat the age of ninewhen we started giving her CBDdominant oilall of a suddenshe started lookingat her parents faceand staringeye contacteye contactthen she started smilingthen she startedtrying to pick her head upand againI get chillsit's 11 years latershe is able to walkin ain a devicethat kind of holds her upso if you canhold up her body weightshe can move her legsand walkshe can use a sippy cupshe can use a spoonto feed herselfshe can manipulatean iPadthis was a childwho was lockedfor nine yearsand think aboutif she could havestarted thiscannabis earlierand I'm going to tell youI still seethat the father is a firemanthe mother quit her jobas an arson investigatorto take care of the childso the community losta womanwhohad a very important jobnow her very important jobis taking full time careof her daughterwhich is wonderfuland how fantasticbut at the same timeimagine if we could have intervenedat a younger ageand maybe mitigatedsome of her disabilityand this is still happeningof courseand one of the thingsthat I have seenand I don't really saythis very oftenI don't like to tell peoplebecause I don't liketo give false hopebut what I have seenwith some childrenwith some autismis theythe earlier I use itif they come to meat a young agelike three, four or fiveit seems thatas they get olderthey use less medicinethe parents are likewe stopped itwe ran outor we went on vacationwe didn't knowif we could bring himwe didn't want to bother youwe didn't tell youor we justand you know whatwe noticedhe's sleeping at nightI said greatdon't use itif he's sleepingrightbut then puberty hitsand puberty can be very difficultfor seizuresand autismand so onbutwe have not exploredwhat these compoundsmight doif introduced earlyand correct that alterationremember what I told youchildren with autismdon't make enoughof their own innercannabis-like compoundtheir endocannabinoidimagine we replace it earlywould it change their prognosis?So it's not likeif you use ityour body stops producing itand you kind of getthen have to stay on itwe have noevidenceof thatso it sounds likeyeahyou can correct itand then maybebut at the samewe knowyeahbut you don't need to stay on itI'm going to share with youthat once your endocannabinoid systemgets into balanceit's like putting oil in your carit runs betterso once you get into balanceI hear this all the timein my adult side of my practiceyou know I don't need as muchand then I saywell what's going on in your life?well really not much has changedI just find I don't need as muchbecause I don't need as muchbecause the tank was emptythe tank got fullyou got into homeostasisor close to ityou don't need as muchto stay inand my analogy there isif you're out of shapeand you go to the gymon day oneare you in shape?noyou're going to go a few monthsbefore you get into shapedo you have to go all the timeonce you're in shape?no you just do maintenanceonce you're in shapeit's easier to maintain ityeah definitelyand so it's the same ideaso that's goodbut with theautistic kids for exampleI meanare they then continuously on itor have you been able tosome are stay on itto manage theirsome kids if they miss a doseall hellyou know all hell breaks loosefor some kidsit's you knowfor whatever reasonthe parent decided to stopthey went on vacationusually it's some reasonthat they stopped itthey didn't stop on purposesome families do askyou knowshould we take a break from itdo you want to go backand here's anotherkind of a patient storyI had a gentlemanthat came to see mewith severe migraine headacheshis whole lifethey had come upwith a medicationthat was an injectablethat they would teach the patientto do the injection at homehis insurance coverednine injections for the monthwell he used to get15 headaches a monthone every other dayor one that lasted a few daysand so he said to meI find myself hoardingthe nine injectionsbecause I'm going to save myselffor the worst headachesnow imagine youso he's sufferingso he comes to see meI hear this worksmy sonmy adult sonis pushing mepushing mepushing mego dadgoI spend timeI educate every patientthat comes inon the endocannabinoid systemI draw a pictureon a piece of paperI teach themall of itI spend an hourhour and a halfwith a new patientto educateand thenyou knowyou need to do the educationif you want good resultshe had complete resolutionof his mindmigrainesdo you knowafter the first two monthswe founda particularoil that washalf CBDhalf THC50% of eachno migrainesafterokno injectionsanythingno injectionsa year lateramazinghe doesn't come backin Californiaat the timeyou had to sign upevery yearyou had to makeyou had to have a check-inyou don't get a prescriptionforeveryou have to go check-inat least minimumonce a yearI didn't hear from himI didn't see himok maybe he movedwhateverbecause we would calland we call our patientsto give him a reminderthree months laterhe came to see meand he saidI thought I was curedI didn't have migrainesand I got one last weekand it was badI saiddid you stop using the cannabishe saidyeahthe letter expiredso I didn't use it anymorehe saidI thought you cured meI saidsee you knowthis is built into your bodythis endocannabinoid systemdysfunctionand soit's just somethingthat you're gonnaprobably have tofeed your system withlow amountsjust to stay in homeostasisand what I believeis after thoseyou knowhe stopped using ithis body trendedtowards hischemistryhis root causefor whatever reasonwhy does he get migrainesprobably geneticand probably someenvironmental triggersbutso he foundthat he needed itbut are there peoplewho find that it kind ofhelps them throughand then they don't need it anymoreyesthere are peopleandone of the thingswe have to rememberwe're not all madewe're not all made the samewe all have our ownindividuallike our fingerprintswe're individualin the way we respond to thingsbut I need tojust come backto the side effectsoh surebecause it's sounbelievablethat I meanthey wantyou knowthe cannabisshouldn't have any side effectsbut then you havethe medicationsand the pillsand especiallywhen we come tothe autistic kidstaking psychiatric drugswith soI meanif you just gogo throughwhat you have experiencedI meanpsychiatric drugsand the side effectsand then cannabis side effectswell we talked aboutthe psychiatric side effectssee there's all kindsweight gainmetabolic syndromeirreversible tremorhypertensionand so onand somany cliniciansare reluctantto even prescribe thosebut you really don't have a lotand very difficultto come offyeahvery difficultto come offabsolutelydiscontinuation syndromei.e. withdrawalyesbutthis is what II share with peoplethe number oneside effectof CBDreally isif you take too muchyou can be sedatedfor some peoplethey get a littleGI upsetwhich even could just beat the carrierthat the oil isthat may not agree with youor you're takinga large volumeyou need a moreconcentrated formulationCBD caninteractwith a numberof medicationsbut surprisinglyit's justnot a huge issueif you knowwhich medicationsto screen forit canelevateliver functiontestsin some patientsin my practiceI just do notsee it very ofteneven on childrenwho are takingother drugsthat could causethe elevatedliver function testsand then there'swith THCof coursewhat are the side effectsso there's a slewof side effectswith THCand they're usuallywhat we calltemporarycan you just explainI think maybesome of ourlistenersare notI mean even thoughwe've askedpreviousumumumintervieweesabout thatjust if you explainTHCand thenI mean allthe differentyou knowjust verysimple explanationon those chemicalsthat we have beentalking aboutthat are partof the cannabisplantsureso THCis theso the plantitself makesas I saidhundreds and hundredsof compoundsthere is a familyof compoundscalled cannabinoidsor what we callphytop-h-y-t-ophyto cannabinoidsplant derivedcompoundsphyto cannabinoidsumthere isright nowI thinkidentified160whateverbook you look atis differentbut it's around160 of themTHC is the mainphyto cannabinoidthat the plantmakesTHC stands fortetrahydrouhcannabinolit isthe compoundin the plantthat will binddirectly towhat we callyour cannabinoidreceptorand if you takeenough of itwhich you don't needto take a lotbut you can feelalteredrightimpairedintoxicatedhigh stonedwhatever wordyou want to useokaybut there aremany many manypatients who takelowumnon-impairing dosesofTHCso it's notall or nothingokaythere are patientswho are able to takeandin childrenwith autismthey are deficientin theirinternalendocannabinoidcalled anandamideanandamideand THCmimic each otherumweI cannot givea childwho's deficientin anandamideI cannot give themanandamidethat's notsomething that'savailablebut we can useTHCand what we startis very low dosesand we titrate upI have some childrenwith severe autismwho takehigh dosesof THCwithout anyevidence of impairmentthe tank isemptyI hope that makes senseso you couldusewe start very lowand we titrate uptothe desired effectbut you needumTHCin my experiencefor the most partthere are outliersbut I includeTHCin just aboutevery single person'sregimenespecially if theyhave autismif they have epilepsywhat we've learnedover the yearsis these compoundscan be usedas what we callisolatesor isolated compoundssingle molecule compoundsbut mother naturedidn't give thatto usno one everhands me an appleand saysdoctor can youtake out the onevitamin in thereno you eatthe whole applethe plantmother natureis smartmother naturegave us this plantwith all of thesecompoundsnow I will saythat when it becameillegaland you think aboutwho would growan illegal plantand potentiallylose their homego to prisonfor many yearssomebody who's a bitof a rebelnot meI'm a chickenumbut they wouldgrow the plantand becausethey were afterthe highthey would manipulategeneticallyyou knowbreed the plantto go higherTHCit's a thingrightwe know this is a thinghigher THChigherhigherhighermore is not always betterI prefer a balanced plantCBD plus THCrightbut at the same timeeveryagainevery person is differentin how they respondand the way youstart somebodythere's a little art to itwhat calledthe art of medicineand you start withwhatI always start patientson what I thinkbased on the scientificresearchplus my clinical experienceI explain that to the patientwe're gonna start herebecause I need to seehow you respondyour feedback to metells mewhere to go nextit's kind ofyou learn aboutthese compoundsyou learn how people respondso let's sayin a childwho starts takingCBDlet's say for autismand the parent says to mehe is climbing onswinging on the chandeliersyou made him worse doctorwell usuallyusuallyalwayswarn the familyCBD in lower dosescan be a little stimulatingif you're alreadyoverstimulatingI might stimulate you morebut we knowthat CBDin higher dosesis more calmingnow the average parentwould sayif I gave a low doseand my kidsbouncing off the wallimagine what a high dosewould dobut nocannabis is very interestingwe call itbiphasicat low dosesit can do the oppositeof higher doseslow dose THCcan be very nicefor anxietyhigh dosesparanoid and anxiousrightso you have to pay attentionyou have to understandthe compoundsand understandhow somebody mightrespond to themit's challenging workit's veryclinical intensiveand laboriousbutthe whole key isif a parentor any ofeven my adult patientsif they can keep a logand report back to meI took thisat this doseand this was my responsewe can pretty muchfigure outand sopeople can't see mebut I'm holding my handsvery widethere's this many optionsand for each personwe want to narrow it downto a regimenthat gives themthe best possible responsewith no side effectsand we call thatthe minimum effective doserightand then I teach peoplewell if you're havinga panic attackso you have a breakthroughyou can have a littlevaporizerto take a puffand relax yourselfa breakthrough seizuresome of my parentstake THCon their fingerrub it on the child's gumsand can help stop the seizurea little bit earlyso there'slike I saida very flexible medicineyou can use itas a maintenance medicinedailyand thenfor breakthrough issuessome peoplesome of my patients sayI only take itif I havea stressful dayat workthen I'll use itwhen I come homeif I don't havea stressful dayI don't take itso it can be takenten times a dayor once a weekor once a monthI meanlike what other medicineis so flexibleso it soundsalso likea beautiful cooperationbetween youand the patientandor you and the parenthas to bea cooperationbecause that feedbackso it's not justyou telling themwhat to doit's a constantand it's not ahere's a prescriptionsee you in three monthsthat is notwhat it isand usuallywhat I'll tellthe family isand I stress thisbecause it drives me crazyyou knowpeople pay mefor this workI want to get youto the right placeas soon as possibleso that you canfeel betteryour child can feel betterpeople sometimesdon't give feedbackthey wait for the appointmentI saidwhy didn't you call metwo months agoI meanI make myselfvery availableto my patientsthe most side effectsare in the first few monthswell of coursethat makes sensethat's when you're trialingyou're trying to figure outam I a low dose personam I a high dose personwe give patientsinstructionsafter this weekyou go up to this doseafter this weekyou'll go up to this doseif you have this side effectyou're going to call mewhat's interestingis thatwe as humansbecause we haveour endocannabinoid systemand because this plantis naturalit sounds all hippy dippybut when you think about itwe acclimate to itokayespecially ifwe have a sayingstart lowand go slowyou start very low doseand I tell peoplethat low dosemay not do anything for youbut if I slap youon a high doseand you have a bad side effectyou're not going to be too happyso we're going to start lowwe're going to be patientand we're going to titrate upand see if you'rea body responseand I'm going to tell youI see a 70 to 80 percentresponse ratein my practiceacross the boardthat's a lotthat's beautifulbut your work hasfocused heavilyon cannabisbut we're also seeingrenewedlike interestmedical interestin psychedelic plantslike mushroomslike psilocybinand DMAand otherswhat do you thinkwhat do you thinkabout their therapeuticpotentialdo they also workon the endocannabinoid systemor is thatcompletely differentit's a little bit differentcannabis really interactsbut rememberthat anything that you takeis going to influenceyour endocannabinoid systemso alsolike the classic psychedelicsyeahand it influences itis cannabis psychedelicthat's a great questionI think for some peoplethey have psychedelic experienceit's a great questionfor some peopleit's very uncomfortableif they take too muchand reallyyou knowit's a funny thingso people ask mewhat about problematicuse of cannabisand I saythere's only onereal storyabout problematic useand that's too much THCokaythat's the problematic useI meannobody's using CBDto get wastedit's justyou're going to be disappointedso it's not going toit'll just make you fall asleepyou'll get a good night's sleepbutbutI thinkthat they all livein their individual spacesbuttogetherwe need to look at itas this renaissancecoming backwe cannot turn our backon what mother nature gives usbecause mother nature existswith usand we should be usingall of theseI have not reallyexpanded into the psychedelicsI've lookedinto itin terms of likesomeone had asked meand paid meto write up a research projecton someon somepsilocybin stuffandvery very interesting to meI don't knowagain because I workwith a lot of childrennobody's there yeteven though I'm surethere are some peopleout there already doing itbut I have not expandedinto thatbut II will share with youone storyI had a patientwhowasis an attorneyhe got COVIDand he ended upwith a long COVID situationthat basicallydestroyed his lifehe would be standingand all of a suddengo downand land on the groundhe would behorizontal in his bedand all of a suddenhave 180heartbeatfor hoursI meanit messedhim upandI know it wasn'tthe vaccinebecause he didn't getthe vaccinehe got COVIDthis was early onhe'd been fightinglong COVIDfor a numberof yearsandcannabis didn't help himnow I've helpedother peoplebut for whateverhe was alreadya cannabis patientand he always saidit was his lifelongmedicinehe felt likeit helped himhe was able togo to law schooland be asuccessfullawyerand also a parentand a husbandand a nice liferightand then COVIDkind of messedthat up for himand I had told himabout some researchthat was being donein another stateand I'm going tokeep it very vagueso nobody gets in troublebecause it's somewhat illegalbut he ended upgoing and havinga true psychedelicexperiencewith a hero doseof psilocybinand then he wasmicro dosingwhen he got backand it changedand he was likeit changed a lotfor himnow is it perfectno but he feltlike about 80% betterso of courseone of the thingsthat makes me crazyis prohibitiondoesn't workstop banning thingspeople will finda wayespecially in natureyeahwhy are welike whowe can havetomato plantsbut we can'thave a cannabis plantlike it just seemsso crazy to meI was sayingto my husbandI meanhow can youban someoneto have likea plant like thisyesbecause this is naturehow can youban natureand then he saidwell what aboutthat cocaine plantI mean what aboutall those plantsI mean there areall kinds ofyou knowbut cannabiswe can't comparewith cocaineor heroinbecauseI don't carewhat anybody saysthere is a dependencebut it's veryvery lowalcohol and tobaccoare much higherso we are beingvery disingenuousby sayingthis plant is badthat just propagatesthat ideathere is no questionthat there areyoung peopleabusing THCwe call thatproblematic THC useall you have to dois engageeducateand we should beeducatinglike I startedtalking to my sonwhen I firstmy son was 8 years oldwhen I startedin this practiceof cannabis medicineand I sat downwith himjá og áðurað við heldumáfrans bjallinuvið dr. Bonnie Goldsteinað þá langa migað minna ykkurá tilbúðinni nettog það er frábærttilbúða núnaá nöytaluntil dæmisá 5599alveg frábærtverðog líka á íslenskuheiðalambifrá kjarnafæði25% afstátturog þvíendilega drýfiykkur þessi tilbúðier til 11. novemberog það er fylltá öðrum flottumtilbúðumog auðvita ölluþessu lífranaflottafrostnuberjanumog reynsifurunumog ég veit ekkihvað og hvaðnú og svo kjarnafæðivið mælum á sjálfsöðuekki bara meðíslenska heiðalambinufrá þeimheldur líkalífrapilisunniblóðmörnumog kjarnaneisvist sviðasöldunniþetta er allt ánaukaefnaalgjörlega reyntog bara eftirgömlu góðuöskruttinnifrájá ég bara með minnirfrá ömmueigandansen við erum náttúrulegaað heyra í eigandanabetur í þessum þættiog hérnaþað er bara áhugaað vera skemmtað sagja kjarnafæðisen svo er þaðlífrana mjölkkurafurog við hefum núómunga þrjú fytusýrumog fytusýri sem heitirCLAþið getur núgooglað hanasem er talin veramjög góð fyrir okkuren þessi munurtengist því meðalannars að lífrana kýriruoftar fóðræðará grasi og hegifremur miklu magniaf svonakornfóðriog oft er þettagetur þetta bara veriðerðabreittinnfluttfóður sem að erþar sem aðeituröfnir erunotið í rektunþví miðurensvo er þetta líkaverið að halda framað það sem sé betrafyrir kýrnargetur jápunar að skilasér í hotlarað aðverðin fyrir neytendurog að auðvitaðer það þannigað því betursem dýrannu líðurog því beturað verða aðverðunarnú og síðasten ekki síster það grínfittmeð heilsumælingarnarog rauði ljósinnsúreifnis meðförðinaogkvöldameðförðinaog það er aðfarja áskriftsvona mánaðar áskriftog koma þaðeins ofta um að villen við skullemhalda áframmeð þettaáhugaverðarspjallvið dr. Bonnie GoldsteinIn the same wayI talked to him aboutyou knowsexand alcoholand tobaccowe sat down about cannabisand I explained to himwhat it wasI never said the worddon't use itor nonever said thatwhat I said isas you're getting olderand you start to becomea teenagerand your bodystarts changingyour brainis verysensitiveto compoundsthere are two timesin our lifewhere our brainsare incredibly sensitiveand that isat the fetal stagewhen they are inthe babies are inour uteruswe want to be carefulwhat we put in our bodyso as not to alterthat brain growthand developmentand then duringteenage yearswhenyou knowfor lack of a better termthe train tracksof executive functionand the maturingof the brainis happeningif you have a puffhere and therethat's not going tomake a differencebut if youstart chronicheavy usein teenage yearsthere is nowa known associationwithmental healthissues laterin lifeespecially ifthere is mentalhealth issuesalready in yourgeneticsso for instanceeverybody talks aboutcannabis causesschizophreniaokayit's not so simpleokayI tried cannabiswhen I was 16I'm not schizophrenicso it does notdo thatif you havea geneticpredispositionand youespecially ifyour motheror first degreerelativehas schizophreniaor they're verysevere bipolarsomething like thatand then chronicheavy cannabisuse on top of thatfrom an early age13, 14, 15heavy usethroughoutincreasesand this is a knownbutsodo you banthe plantnohow abouteducating youthlike I didwith my 8 year oldno chronicheavy useif you wantto use somethingyou come to meand we're goingto talk about itrightbeforehandso it can beused as medicinerightwhen Italk to my sonabout sexI said whenmommies and daddieswant to get marriedand have babiesnot everybodydoes it that waybut I would likemy son to havethat experienceand all of thatso you canplant a seedand childrenare blank slatesyou're nevergoing to tella 15 year oldwho's alreadysmoking cannabisto stopsmoking cannabisand they're goingto listen to yougood luckif you've hadteenagersyou know whatI'm talking aboutand if you justsay nothat's not goodenoughexplain ityour brainis developedand when youplant the seedwhen they're8, 9 or 10when they'reat schoolor at theplaygroundor whereverit isand someonepasses a jointto themhopefullythey hearyour voicein their headand your voicesaidI'm not goingto tell younoI'm justgoing to saybe thoughtfulabout itdon't getinto thisand if youwant to getinto thislet's havea conversationwhy youwant to getinto itis theresomethingbothering youare younot sleepingat nightare youanxiousare youbeingbulliedat schoollikehave theconversationwith yourchildthey deservethatand becauseI meanat thisstagewe arenot eventalking aboutallowing itI meanjustfreely usedlike alcoholwe are justasking fora medicalallowanceto treatpeople with itbecausewe havethe sciencebehind itas wellbut thenaysayerswill saythe minuteyou dothat medicalohit'sI hateto breakit to youthe kidsalready haveitI hadit in the1970swhen it washighly illegalin theUnited StatesI was inNew Jerseyand thefirst dayof highschoola kidnext tometurnedto meI'ma brandnewlikefirstdayinhighschoolhe saysyou needanythingI saidwhathe saysI gotweedI gotsome pillsand nowIranhomeand Isaidto mymotherI haveto changewhere mylocker isI can'tbe righttherethere'sdrugaddictsthereyou knowit'sthereand theonly thingwe candowe can'twishourchildrento notdothingswe haveto discussit withthembut wehave tohave therightinformationand wealso haveto saythatand wealso haveto recognizethat ifourchildrenaresufferingdo wewantthemonpsychiatricmedicationor dowewantthemonsomethingnaturalthatpotentiallycouldmakethembetterfeelbetterwithoutthesideeffectsand theexperienceinCaliforniaI meantheyallowedmedicalcannabisinwhat didyou say19961996yeahso whatis theexperiencetheresotheexperienceinCaliforniaissuchthatyouknowit wasalwaysavailablehavingitmedicallyavailableingeneraland I'llsharewith youso astudycame outlastyearand IposteditonmyInstagramthatactuallyyouthuseisdownokayand thereason Ipostedthatwasbecausesomebodypostedsomethingelsewherethatsaidthere'severykidissmokingpotand they'reallgettingstonedand they'reallgoingtoschoolthatwayand they'reallnothey'renotand infacthavingmakingitlessbadIthinkmakeskidsthinka littlebitIdon'tneedtogothereyouknowwheresomethingislikeforreallyforbiddentheteenagerstendtokindoflikewanttogothatwayandDr.MagnusThorssontheIcelandicprofessorhe washerealsointhepodcastandhesaidalsotheexperiencehasbeenpositivebecausewhenyoulegalizeitIthinkhe wasalsotalkingaboutjustmedicallynotrecreationallybutevenrecreationallythatthatisbeingyouknowthatmeansthatit'slegallikelikealcoholbutinIcelandbutandthinkaboutkidsthatareusingalcoholImeankidsstartsyouknowthedrinkingpartieslookIworkedinpediatricemergencymedicineIworkgraveyardshiftso IcouldbehomeduringthedaywithmychildsograveyardshiftisatnightwhatdidIseewhenthekidscameinonFridayandSaturdaynightalcoholalcoholwastedIhadagirlcomeinnakedpassedoutinanalleywaycoveredinherownvomitwedidn'tknowhernamewedidn'tknowherageIdidn'tknowifshehadbeenrapedIdidn'tknowanythingitwasHalloweentheparentswefinallyfoundafriendcalledinwefoundhernameitwasacrazystoryherparentscameinandsaidwhere'sherclotheswhere'sthisshewenttoapartywhereshedranksothisisnothingnewweneedtoeducateanditcan'tbejustsaynoithastobegivethemalittlebitofthescienceyouhaveasysteminyourbodythatthiscouldbemedicineforyoudon'twanttojustabusethisImeanchildrenrespectwhatwesaytothemwhenthey'reyoungerandwe'reteachingthemweneedtounderstandthatandwecannotignorethatit'sverydifficultoncethey'reteenagerstochangewhatthey'vealreadyseenintheirpeergroupandtheirexperiencebuthealsosaidtheblackmarkethadalsothendecreasedsoitwasmorecontrolitdependswhereyouareinCaliforniaunfortunatelythepricesthetaxesareextremelyhighandsothere'saprettyrobustundergroundillicitstillbutagainit'snotallowedrecreationis itit'sjustmedicalnoinCaliforniait'srecreationalsince2018oksoit'sbothyeahit'sbothbutpointbeingthattheoveralladolescentuseif youlookatthelatestresearchitisdownithasgonedownithasnotgoneupopioidusehasgonedowninstatesthathavethere'saverywellknownstudyfromIwanttosay2015or16wheretheylookedatourmedicareprogramwheremedicareisover65yougetfederalhealthcareoklikehealthcarefor allonceyouturn65andwhattheyshowedwasthatinstatesthathadmedicalcannabislawstheprescriptioncostsforthewhattheycallmedicarepartdthepartthatcoversyourprescriptionswentdowninthismedicationthey'reusinglessmedicationwhodoesn'twanttheirelderlyparenttotakelessmedicationwhowantsthemtofallandalsoIjustthinkit'ssoIjustit'sverybasicImeantheyareallowingtheopioidsandthinkaboutthedetrimentaleffectsthattheopioidshavehadImeanwehavepeopleinmiddleagethathaveneverbeenwhatyousaythey'veneverbeenyeahnowweneedtheEnglishwordaddictedyeahtheyhaveneverhadaddictionImeanwehavepeopleinmiddleagethathaveneverhadaddictionandthentheyareputbecauseofpainsurgeryexactlytraumatheyfellyeahandafterthattheygetaddictedIhavepersonalexperiencewiththatandsomeoneonmyhusband'ssideyeahwhowasaddictedtoopioidsandactuallyhadtogointothehospitaltobedetoxedandaweeklaterwasinterribleshapesheknewaboutcannabisbutshedidn'trestartitandshegotsomesleepingpillsshetookapillandshefellandhitherheadanddiedsomedicationcan beverydangerouscannabisthefearassociatedwithcannabisisunfoundedIamheretosaythatwhenitisusedundermedicalsupervisionifyouareworkingwithsomebodywhoisknowledgeableyoudoandjustIthinkeveryonewhenyoulookintoitit'ssostrangethatyouallowopioidsthathaveallthoseconsequencesalcoholtobaccoallofthemandyoudon'tallowcannabisthatcouldbesomuchhelptopeopleforexamplewithchronicpainrightandsowhatdothestudiesshowaboutthatsowehaveafewstudiesthatshowofcourselikemyreportthat'scomingoutthattherehasbeenareductioninoverallopioiduseinmedicalcannabispatientsrightsomepeopleuseitinsteadofopioidstheytakeitandthey'regoodrespondersandtheyfindorforwhateverreasontheirpainisrespondingwellthere'ssomepeoplewhouseitinconjunctionwiththeopioidthere'ssomeevidencethatthetwotogethercangiveaddedsynergyforbeneficialresultswhyisthatopioidreceptorsandcannabinoidreceptorstheycanlivenexttoeachotheronacellwallandwhenyoutakebothyoucanhavethissynergisticdecreaseinthepainsignalingandthenthere'ssomepeoplewhojustuseitasharmreductionontopoftheiropioidusesotheydon'thavetoescalatetheiropioidsintothedangerzonewheretheycouldpotentiallystopbreathingsocannabiscanbeusedisitinsteadofisitinadditiontoit'salloftheaboveithasthisflexibilitysothatwecanwhenIsayweImeanpeoplewhoareclinicianswhoareknowledgeableinthiswecanhelpyoualongyourpathtofigureoutwhatisitgoingtobeforyouisitgoingtobeafullsubstitutionpartialsubstitutionorjustkeepyoufromescalatingintothedangerzoneIjustImeantherearesomanyquestionsactuallyIreallywouldliketocometocanceraswellbecauseyouhavealsobeenhelpingcancerpatientsandImeanjusthavinggonethroughcancerexperiencewithpeopleclosetomeandseeingthemintheendoflifejusttakingopiatesforthepainknowingforexamplethatbecausewhenyoutakeopiatesImeanyoustopeatingaswellandtherearesomanythingsthatyouknowyougetyouknowthebodyjustyouknowreallyalsoslowsdownsotheyarenotinIcelandhereusingcannabistohelpcancerpatientsbutit'snotjustthatbecausecannabishasbeenusedisn'titalsointherapyagainstthecanceritselfsuresothere'stwowaystousecannabisforcancerandthere'soverlapbetweenthetwosowehaveclearcutstudiesthatshowandIdon'tcareifitdoesn'tneedtobelieveplacebolikeyouweresayingacontrolledtrialandI'mgoingtosharethistomorrowattheconferencethere'sareportthatcameoutin2018fromIsrael2900almost3000cancerpatientswhowerenotusingcannabiswhowerethenrecruitedintouseandwhattheyfoundwassignificantimprovementinqualityoflifesolikeoneinfivepeoplereportedthattheyhadagoodorverygoodqualityoflifewhentheystartatthebeginningoftheircannabisjourneylet'ssayandattheendatsixmonthsthenumberwasmuchmuchhigherlikeIforget70%ormuchhighersignificantinadditiontheyreportedthatpainso53%atthebeginningofthestudyreportedtheirpainwaseitheran8, 9, or10 outof ascaleof10with10beingtheworstandaftersixmonths5%reportedtheirpainbetween8, 9, or1091%reportedbenefitsnauseavomiting88%reportedbenefitsandsleepthenumbersdonotliethesepatientswerenotencouragedtolietherearecancerpatientsthatarestrugglingtreatmentwastoleratedthesideeffectsweremildandwhenaskedaboutsideeffectsbetweenthepharmaceuticalandthecannabistheysaidnotonlywerethesideeffectsfewertheywerealsolessseverewithcannabissotomethewritingsonthewallwhilewe'reignoringitIhavenoideaIjustcannotyouknowbecauseI'msofarinthatIthinkaboutwhatgetswreckedwhenyouareundercancertreatmenteverythingcannabisandyoulosehomeostasisthere'snoquestionaboutthatithelpsitalsohelpswithappetiteandallofthesethingsthere'stonsofthemforcancerandweseethemindifferentcountriesanddifferentpopulationshowisitthatI'mgettingthesameresultsasacolleagueinGermanyisitbecausewe'relyingnoit'swhat'shappeningrightthesecondpartoftreatmentforcanceristhatweknowthatthesecompoundsineitherthetesttubeorinanimalsnotverymanystudiesinhumansbutI'llsharethoseintesttubeorinanimalswhatwehaveseenisthatcertaincannabinoidscankillcertaincancercellssoin1975theyputTHCinatesttubewithlungcancercellsandtheyfoundthattheTHCkilledthelungcancercellsthatshouldhavebeenabreakthroughbutofcoursescheduleonesonotallowedtostudyitcan'tdoanythingwithitrightnotthebenefitsbutweknownowthere'saverylargebodyofliteratureatleastinthetesttubesowhatwecallpreclinicaltesttubeandanimalstudiessoimplantacancerahumancancercandiethere'salsoevidencesoandthisiswhatweknowthatcannabinoidscaninhibitcancergrowthtojustsumitupcancausecancercellstocommitsuicidethat'scalledapoptosisitcanstopcancercellsfromspreadingwecallthatmetastasisrightsoCBDinparticularcancercellssendeachothersignalsgospreadgoyouknowbefruitfulmultiplyrightCBDhasbeenshowntoblockthosemessagesthere'salsosomethingcalledtheantiangiogeniceffectsangiogenesisangiobloodvesselgenesisbirthofbirthofbloodvesselsit'sgrowingrightbythetimethatacanceristhesizeofthetipofaballpointpenitisalreadygrowingitsownbloodvesselstofeeditselftohijackyourgoodiesinyourbloodstreamtofeeditselfCBDisantiangiogenictherearechemotherapiesthatantiangiogenicwhywouldn'twelookatCBDbecauserememberone ofthebigthingsisthesecannabinoidsdo notharmhealthycellswhatachemocanharmhealthydoesn'ttellthedifferencebetweenhealthycellssothatishugerightwealsohaveresearchthatshowsthatcannabinoidscanenhancetheeffectsofchemotherapyokayand wealsoknowthatcertainchemotherapieswhencombinedand yousawa casein achildinthatmoviewereadthepeopleofayoungmanwhowasundermycarewhohadstagefourosteosarcomaaterribleterribledevastatingbonecancerhecametomewithaftermultiplesurgeriesmultipleroundsofchemotherapyhewassenttomeforpainmanagementaftertheparentsweretoldhewasnotgoingtolivemuchlongerandtoprepareforthattheoncologistsaidgoseeDr.BonnieGoldsteinshe'llhelpyouwiththepainbecauseIcan'tgivehimanymoreopioidshe'sonthemaximumdoseandit'sgettingdangerouscryinginpainayoung16yearoldyoungmanfightingcancernowfortwoandahalfyearshecametomeI'llneverforgettheparentssittingtherethemotherworksforakindofacompanythatworkswiththegovernmentsoshewaslookingatmelikeI'madrugdealerokaylikedeerintheheadlightsthefatherjustwantedtoknowthedetailsjusttellmewhattodotosavemykidslifeandIwaslikewellyouweresentforpainmanagementIsaidIcanmakehisIthinkwecanmakehispainbetteryouknowIneverpromisedbutIsaidbutheisonhewasstillonwhatwecallpalliativechemotherapytheyweren'treadytowithdrawtreatmentasaparentIunderstandthisbutalsoasaparentIwilltellyouIhada14yearoldinmyhouseandthiswasa16yearoldandIthoughtIwouldnotgodownwithoutafightI'mnotlettingmycancergetmykidsowhenItakeonakidthey'remykidbringstearstomyeyesandIexplainedtothemthatthechemotherapythathewasonthereisastudyinanimalsthatshowedthatcannabisplusthatchemotogetherkilledcancerbetterthaneitheraloneandwhyshouldn'twegoforitandIknowtheylookedatmelikeIwascuckoobecausetheironcologistwhowasbrilliant30yearsoncologywonderfulwomanwonderfulshesenthimherejustforpainmanagementbeforehediesandthisdoctorisgoingtotellmethatthere'sachancelikewhatdrugsissheonrightandIsaidbutittakesacouragelikeforyoutogobutIgetangrybecausehowyouletakiddieifthere'sachance1%chancewhydon'twetryIwouldwantthatformychild0.2%chanceI'mgoingtotrysoatthattimethekindofcannabisIwantedhimtogetwasalittlebitdifficultit'sveryconcentratedhighdosehedidnothavealotoftimeleftIdonothavetimeand CBDtogetherhalfand halfas muchas hecouldtolerateatleasttoacertainamountthetypicaldoseofTHCformostpeople2.5milligramstoaboutsomepeoplehigherforpainandwhatnotwetitratedhimupover4weeksto500milligramsadaybecausehisgutwasdestroyedandIknewhewasn'tabsorbingitbecausehewasaboutasskinnyasmypinkyfingerhehadbeenonchemo2.5yearsimaginethemicrobiomedestroyedhisarmswereveryskinnyyoungmanfromyearsoftreatmentsoWe startedhim onthecannabinoidsand Idid sayyou knowgonna startherebut itwas stilla highdoseand theparentstold methatwalkingdownthehallwayfromhisbedroomtothebathroomwasa littlechallengingbecausehe wouldbumpintothewallshewasstonedbuthe'sadyingkidIdon'tcareifhe'sstonedwhatamIgoingtoworryaboutthatwhenhe'sdyingtryingtosavehislifeafteroneweekhewasdownIthinkontheopioidsbyalmostmorethan50%infactIthinktheparentssaidhewasdowntooneortwopillsadaythehighfevershewashaving104feversfromthecancerbeingoutofcontrolandbytheway20tumorsinhislungsitwasinhisbonesvertebrahecameinmyofficetoholdhisneckbecausehehadvertebralsurgerytopullatumoroffthatwaspressingonhisspinalcordImeanlikeasickdyingchildandtheystartedthattheytextedmeoncetoaskaquestionisitokifhetakesitnowhe'seatingagainsocanwegiveittohimwiththefoodofcoursehow'shedoinghe'salmostofftheopioidsandheseemslikehe'sfeelingbetterIsaidokkeepmepostedhighdoseandIgavetheminstructionstotitrateforoverfourweeksandthenjuststayIgavethemwhattheycallagoaldoseokandI'vebeendoingthisforafewyearsalready2008thisis2015sohecameApril2015inJulyof2015IgotatextmessagefromthemotherDr.GoldsteincallusrightawayandIthoughtohnowhathappenedandIhadaparticularlydifficultdaythatdayinmyofficebecauseIhadanopioidaddictthatwasverydifficultlet'ssaythehusbandwastryingtogethiswifeoffopioidsshedidn'twanttobetheresoIwaslikeit'sveryhardtotrytosayopioidsarepoisonit'sgoingtokillyouI'mnotgoingoffofitsoitwasastrugglethatdayrightoneofthosedaysandthenyouhadtomakethecallImadethecallDr.Goldsteinyou'renotgoingtobelievethishejusthadallhisscansthere'snoevidenceofcancerthreemonthslaterthreemonthslaterwowthatwas2015whathappenedohhe's27or28nowandgoestocollegeandhasalifenowhe'sdamagedhisfingernailsareallmessedupfromthechemohe'salivetheonlythingyoudidisyouputhimonaveryhighdoseofcannabisIsaidIknowaboutthisstudyinmicewiththiscombinationwiththischemoandifitweremykidthisiswhatIwoulddoandIexplainedittotheparentsIdon'teverIdon'tselltheproductsoI'mnotgettingrichofftheproductrightIjustIhaveonefeeyoucometomeitcoversyouforawholeyearoftreatmentit'sveryreasonablesohewasalreadyonthischemotherightchemopalliativewellIwouldn'tsaytherightchemoitwasthechemothattheyweren'twillingtotakeawaybutitwasn'tcuringhiscancerwhenIaddedthecannabisthenwesawthecancergoawaysothequestioniswasitthecombinationwellI'dlovetodoastudyifanybody'souttherelisteningandwantstodoastudyfeelfreetoreachouttomebecauseIstilldon'thaveastudytothisdaydoyouknowthereareliterallytwostudiesoncannabisandcancerinhumansclinicaltrialsreallytherehavebeennoneandifwewhywouldn'tyoutryit'ssomeone'sbrothercousinmotherfatherdaughterbutwhyisn'titdonebecauseImeanbecauseit'snotconsideredstandardofcarebutalsoI'llbehonestwithyouit'sbecausenobodycanownthepatentonfullspectrumcannabisandalsobecausepeopledon'tknowaboutitbecausetheprofessionsarenotcommunicatingitsowhatyou'redoingisprobablyhelpingspreadthewordandwhenthepatientsknowthey'regonnayeahIhavea lotofcancerpatientsthatcometomeandthere'snoquestionthatsomepatientsitdoesn'tworkthey'remaybenotonthatchemotherapymaybethat'sthespecialsaucerightI'vehadotherpatientswhosaidtheydidn'ttakeanychemoandIhaveapatientwhohadanadultpatientwithmelanomaandsheusedaplantbaseddietandcannabisandshehascuredofhermelanomashedidn'tevenhavehealthinsurancesoshecouldn'tevenreallygoshehadtopayoutofpocketandshepaidanintegrativeoncologistsosheusedcannabisandsheusedafewothersshe'spublishedsomebooksandshehaspublishedbookafterwardsshewritesbookslikeshesentmeherbookonshemakeslikeplantbasedsoupsandsoshesentmeherbookandsheputalittlethingintherethankyoutoDr.GoldsmithandabunchofotherpeopleItookcareofalittlegirlwithleukemiawhohadgottenachemothetypeofit'snotjustonekindofleukemiaofcourseshehadaleukemiageneticleukemiathatwasveryaggressiveandshegottreatmentshegotabonemarrowtransplantandrelapsedthreemonthslaterandtheycametomeatthreeyearsofageanymedicalinterventionistortureforthesechildrenthey'regettingputtosleepit'sterriblewhen achildisillbecausetheydon'tunderstandthefamilycameandtheysaidwedon'twanttotortureheranymorelikewecan'ttortureheranymorewiththehospitalsoherbonemarrowtransplantdidn'ttakeweputheroncannabismedicineandbyaboutweek10therewasnoevidenceofherleukemialeukemiaseemstobehighlysensitiveifyoureadtheliteratureinthepreclinicaltesttubeandanimalsagainwedon'thaveclinicaltrialshighdoseshewentintoremissionornoevidenceofleukemiaandthenIrememberaboutmaybefivemonthsinsixmonthsintheydidabonemarrowbiopsythatwasgiventohertotrytosaveherhadactuallyengraftedintoherbonemarrowtherewasnoevidenceoftheleukemiaandherbonemarrowtransplanttookeightmonthslaterIgot acallfromthefamilythecancerisbackandIsaidwhatdoseissheonIhaven'theardfromyouguysinforeverusuallygoodnewsnonewsisgoodnewsdoyouknowwhattheysaidtomewestoppedthecannabiswhydidyoustopthecannabiswelltherewassomedisruptionbetweenthemotherandfatherandtheyjustdecidedtostopthecannabisandunfortunatelyshegotleukemiaagaintheystartedheronchemoandshegotaninfectionthatshediedfromaninfectionbecauseyouknowthechemowipedoutherbonemarrowsoshediedandit'sjustheartbreakingtomeanditmaystillbetherebutwecan'tseeitpleasedonotstopthecannabisbecauseitappearsthatthereissomeevidencethatwhydopeoplegetcancertobeginwithandwethinkit'sanimmunedysfunctionandcannabinoidshavebeenshowntohelpmodulatetheimmunesystemandputitintohomeostasisweusedtosaythatcannabinoidssuppresstheimmunesystembutitturnsoutit'smoreofahomeostaticmodulationsowhywe'renotdoingtonsandtonsandtonsofresearchisbeyondit'snotbeyondmeit'saboutthepatentabilityandtheabilitytomakemoneyonthatsoyeahandmaybethere'snobodyputtingmoneyintotheresearchbecausetheycan'townityeahnothere'sthereandsonowintheUnitedStatesthatit'sbeenkindofshiftedtoschedulethreeoneofthebiggestthingsofcourseiswecanstudythebenefitsbuttheproblemiswho'sputtingmoneyintothatwhere'sthosefundscomingfrompharmaceuticalcompaniesarepursuingcannabinoidsthey havepursuedthembutitisinapatentedwayithastobetheabilitytopatentittheyspendahugeamountofmoneyrightthere'ssomeproductsthatareavailableisolateCBDisolatesbeenapprovedintheUnitedStatesforchildrenwithcertaintypeofepilepsiesthreetypesofverysevereepilepsyanditisait'sanisolatesoit'ssinglemoleculeCBDwithafewothercompoundsfromtheplantsveryhardtoisolatecompletelybutlookI'mallforitifapatientcangetaprescriptionandithelpsthemfinegreatgopickitupatthepharmacyeverythingshouldbeonthetableforsickpeopleeverythingbuthowhasthischangedlikeyourlifeyourprofessionallifeyouspentabouthalfofyourprofessionallifeinthemoretraditionalpediatricemergencymedicineandthenyoumaketheshiftintothisIdon'tknowwhattocallitkindofmedicinewhatdoyouthinkithasmeantforyoupersonallyandyourrewardingjoboh mygoodnessare youkiddingsolikesuperrewardingfrustratingattimesofcourseImeanIgetfrustratedand youcan hearI'mraining itin todayso it'sbe niceon yourpodcastbut IgetreallyfrustratedIgetsuperfrustratedwhen IhearsomebodydiesandpotentiallywecouldhavesavedthemthatbreaksmyheartIrememberawomancomingtomeforsomethingandshehadheradultsonwithherIdidn'tknowthatthehusbandhadpassedawayfromcancerbutthepatientthemomhadaskedmea fewquestionsaboutcannabisandcancerandIkindoflikeyouknowblahblahblahwhatmylittlespielisandtheyoungmanturnedtohismotherhesaidyoumeandadcouldhavelivedandIjustdon'thavealittlegirlinmypracticethathasararesyndromecalledacardisyndromeit'ssomewhatdevastatingIstartedtakingcareofherwhenshewasthreethefatherisareligiousmanapastorandtheystruggleda littlebitwhentheyfirstcametomebuttheyrealizedthatthewaytheyreconcileditisGodgaveusthisplantonearthandGodgaveusanendocannabinoidsystemsowhywouldGodgiveusbothofthoseandsaydon'ttheyshouldhavenothingtodowitheachotherandthat'sandIhadaskedthemomIhadbeeninvitedtoaconferenceandtheysaidmaybeoneofyourparentsmightcomeandspeaksoIhadjustrightbeforetheycouldn'ttravelanywaytheyshowedupandthemomspokeandsheshowedpicturesofherdaughteronthescreenshehadtheentireroomintearsthischildwentfromfiveseizuremedicinesthatdidnotcontrolherseizurestotwoseizuremedicinespluscannabisbothofthoseseizuremedicineswereloweredtotolerabledosesthatdidn'tcausehertojustsleepalldaylongshe'sverydisabledchildshestoppedhavingtogotothehospitaltheystartedbeingabletobringhertotheirtheyhadtwooldersonsbaseballgamessoccergamestheywereabletotravelwithherbecauseshewasn'thavingseizurestheyrecentlyrelocatedtoanotherpartofCaliforniaandtheywenttoamajorchildren'shospitalthathasaclinicandthere'soneoftheepilepsypediatricepilepsydoctorsthatthatisfocusisonthatparticularsyndromeacardisyndromeandwhentheywentinsoonthefirstvisittheysaidsotellusaboutherhospitalizationsandthemomsaidandshe'snow14soIstartedwithwhenshewasthreemomsaidwellwehaven'tbeenhospitalizedforseizuresandthedoctorsaidwhatdoyoumeanyouhaven'tbeenhospitalizedforseizuresshesaidwellwe'vehadsomeGIstuffsomegastrointestinalissueswhereherstomachkindofbecameparalyzedonetimefromanillnessandthefoodcouldn'tgothroughandshewasvomitingsowewereinthehospitalforthatbutweweren'tinthehospitalforseizuresandthedoctorsaidwellgoshyouknowlikethat'sveryrareandthemomsaidyeahwellit'sbecauseshe'sbeenoncannabissinceshe'sthreeandthedoctorsaidwellitmustbeaverymildcaseofacardisyndromeandshesaidnolistentomethisiscannabisinterventionatagethreethisisayoungladywhoactuallysaidIloveyounowitdidn'tsoundlikewellIdon'twanttosayitdoesn'tsoundlikeIloveyouwhenIsayIloveyoubutshewasabletosayIloveyoubutonedaythemomhadtextedmeandshesaidshe'sjustholleringnonstopandshesaidandIcouldn'tfigureoutwhatwaswrongshewantedtogoinhercarseatinthegolfcartshesaidIcouldn'tfigureitoutIchangedherdiaperandthisisyouknowshe'saverydisabledchildbutshewascommunicatingIsaidIthinkshe'stryingtocommunicatewithyoushesaidyeahIpickedherupandIputherinthegolfcartandwetookarideandshewassohappyshewastryingtotellmeshedidn'thavewordsthoughshesaidshe'sneverdonethatbeforeImeanthisisanditsoundscrazybutthisismyexperienceandIwillsharewithyoutheparentspayoutofpocketalotofmoneyforthissomeofthemgiveupotherthingstobeabletobuythismedicinefortheirchildrennobodywoulddothatifitwasn'thelpingsoandwhenitdoesn'tworktheytellmesowehavetoremembernoteverysinglepersonisgoingtorespondbutanybodywhoisstrugglingshouldhavetherighttousethismedicineatleasttryitexactlyhereinIcelandbecauseinEnglishwecallthisdrugsandwespeakaboutillegaldrugsorcontrolledsubstancesorsomethinglikethatbutinIcelanditsoundsevenmoredangerousbecausewehavethiswordforeiturliðit'sreallyacombinationofthewordspoisonanddrugsoweevenwecallreallynegativeyeahit'slikehighlynegativesoweusethatwordeiturliðevenforcannabisandforpsilocybinandforMDMAwhichliketo mesoundslikeveryveryyou knowscaryyeahscaryyeahandI'mgonnasaythatthere'snowonderthatthepublicinIcelandthinkswe'retalkingaboutlikepoisondrugswhenwespeakaboutcannabistherearefamiliesIhavemetmomswhosaycannabisdestroyedmychild'slifetheystartedusingityoungandtheygotaddictedtoitandtheyneverdidschooltheyneverdidthis100%butthatdoesnotdenyitsmedicinalvalueforsomebodyelseandopioidsdestroylivesandwestillprescribethemsotherecannotbeonestandardforonedrugadeadlydrugandthenputthatstandardontocannabisthatisnotokaywehavecannabishasitsownstandardandI'mjustgoingtosaythisthatundermedicalsupervisionespeciallyit isincrediblysafeiftheworstthingthathappensisyoufallasleepyouwillwakeupandsaywowI'moutofitbutIsleptrightImeanwhocan'tuseagoodnightsleepbutatthesametimethatdoesn'tmeanIwantteenagersabusingitandI'mnottalkingaboutthatI'mtalkingaboutmedicaluseforsomebodywhohasamedicalneedI'mjustthinkingit hasbeenI meanabsolutelymindblowingto listento youand yourexperienceand Ithinkmanypeoplethat arelisteningI meanthey hadno cluethatcannabiswould beso potentI meanagainstsomanymanymanythingsandImanyjustpeoplelearningaboutthisfor thefirsttimeandIthinkthisisopeningupbutstillhereinIcelandthisisillegalwehavethecannabisoilsbutCBDoilsbutwithouttheTHCandfromeverythingthatyouweredescribingtheTHCisalsoaveryimportantchemicalinthehealingprocessofthepatientsthatyouhavebeentreatingsoI'mjustthinkingI meanI'mnotaskingyounowtogivepeoplesomecriminaladviceherebutwhatcanpeopledoImeanpeoplewithautisticchildrenthatwouldliketotrythisorImeanpeoplewithcancerorthey justhavetomovetoSouthernCaliforniacomeseemebutthereareareadvocacygroupslikethisyou knowhealthfor thefuturethatwanttosharethesciencebehindthisIthinkthefirstthingkeyistobecomeeducatedI'vehadtheveryrewardingandhumblingexperienceofhavingapediatricneurologistreachouttomeandsayyoudon'tknowmebutIreadyourbookandIstartedtreatingpatientsandguesswhatyouwererightandIwhenIstartedthisIyouknowwhathesaidIgotyourbookanditsatonashelfforsixmonthsbeforeIevenpickeditupandthenIreaditandIthoughtwellshedoesn'tseemlikeshe'scrazysomaybeitwillhelpandthenhehadaparentwhocametohimandsaidpleaseIhavetwochildrenwithautismwillyoupleasehelpmepleaseandhetoldmeshetwistedhisarmthatmotherpushedandtwistedhisarmandnowhehasseenalmost300patientsandhe'spublishingdataonhowcannabishelpschildrenwithautismsleepbecauseoneofhisinterestsissleepmedicinehe'sboardcertifiedinpediatricneurologyandsleepmedicinesohestartedlookingandhesaidthere'snothingpublishedonsleepandautismhewasgettingnumbers70%80%similarnumberstomeIwasdoingithereachedouttomeafterhealreadycollectedallthedataandsaidyouhavebeenmentoringmefromafarIdidn'tknowyoudidn'tknowmebutIknewyouhepresentedhisdataataconferenceinJuneandIwasblownawaybythatthathere'ssomeonewho'sadamantit'snotapprovedbytheFDAit'snotapprovedbytheAmericanAcademyofPediatricsit'snotapprovedbytheAmericanNeurologyAssociationbutyethelethesaidI'lltryitwiththisonemomwho'swillingtodoitandit'snotgoingtosuemeifIgetitwrongandwhathesawwasthosekidsgotbetterandhestartedusingitinhispracticewhatweneedisjustforsomedoctorstohaveopenmindrightbutalsotheirsistertheirchildwhoissickwhoisbeingundertreatedbythecurrenttoolsthatwehaveinourtoolboxthewayIlookatcannabisit'sanothertoolinthetoolboxandwearesmartenoughtounderstanditwhyareweafraidofititmakesnosensetomejustunderstanditandwhatwedon'tunderstandlet'spushforresearchinthoseareaswearesmartenoughtounderstandthisthesamewayweunderstandothernaturaltreatmentsbutI'mthinkinglikehereinIcelandifpeoplewanttotryImeancouldtheygetalsoresultswithonlytheCBDit'sagreatquestionsotherearegoingtobesomepeoplewhorespondbeautifullytothecannabinoidsandI'llgiveyouaforinstancethatwaspublishedinastudyin2018therewasastudypublishedreportsaboutfullspectrumoilandtheyhadfrompublisheddata670patientstotalfrom11or12differentstudiesandwhentheypulledtheresultswhattheyfoundwasthatnotlookingatanydefinitionthecannabinoidsreducedtheepilepsywhenitwasfullspectrum73%versus40someoddpercent46%forthepurifiedso46%ofpeoplestillgotitstillI'malsothinkingmaybeforsleepandfortheaggressivenesswhenyouusepurifiedyouhavetousehigherdosesbecauseyouhavenosynergyamongstthecompoundsit'sthatideaagainofpullingthatcompoundoutoftheapplerightI'llpullthisonevitaminoutmothernaturepackageitthewayshedidforareasonsoIknowitsoundsweirdtosaythatasanMDbutwhywouldIwanttotaketheplantandmanipulateitnowthere'salwaysoutliersinmypracticetherearepeoplewhodonottolerateTHCthere'spatientswhodon'ttolerateCBDandonceyoufigureoutwhothatpersonisthenyoujustmoveawayfromthatbutlikeIsaidthere'ssomanyothercompoundsintheplantIuseTHCCBDCBGTHCACBDACBNCBDVTHCVI knowI'mmissingsomeCBGAthat'saboutitsoIhaveninedifferentcannabinoidswhen ItalkaboutthatdominantrightsowhenyouhaveawholespectrumyouhaveadominantcompoundoryoucanhaveabalancedyoucanmixtwoplantstogethersosomepeopletakeadominantTHCandadominantCBGandtakethosetogetherbutyouhavemanyhundredcompoundsintheplantsowhenyousayalwayscountingthoseasjustkindofthedominantcannabinoidsthat IwillrecommendtopatientsbecauseIunderstandwhatthosedobutremembertheycaneitherbeanisolateorwithinthefullspectrumthewaytothinkaboutfullspectrumforjusttogivepeopleareallygoodanalogyisdoyouguyshavechilihereyesokaysoyouhavechiliwhenyoumakechiliyoumighthavemeatandbeansandawholebunchofotherkindofsmallingredientsspicestogiveitflavorrightandinthelikemaybeatomatobaseorsomethingifIweretopulloutthemeatthatwouldbeanisolatemeatsoifIweretosayCBDisolatethat'sjustbyitselfwhenyoutalkaboutfullspectrumCBDisthemeatinthereTHCisthebeansthemaintwobutthenawholeslewofotherminorcompoundsthataddtotheflavorlet'ssaythat'skindofthewaytolookatitthere'sgoingtobesomepeoplethatcan'ttoleratethewholechilimaybetheyhaveirritablebowelsyndromeorsomethingortheyhaveceliacdiseaseIdon'tknowsomethingandyouwouldjustsayohwe'lljusteatthisrightbutforthemostparttryforthemselvessothat'satrickyquestionformeasaclinicianokayIwouldsayitisalwaysbettertoatleasttalktosomebodywhoknowssomethingoreducateyourselfreadabookwatchmyvideosIhaveabunchofvideosonYouTubeIjustsaytrytoinvestigateit'sreallyaninterestingmedicineinthattherearepeoplewhocanselfmedicateandgetverygoodresultsforthechildrenwithpneumoniaIwouldnothandyourchildthekeystothepharmacyandsaygopickoutyourmedicinewhatwouldtheyknowrightit'salwaysbetterunderclinicalguidanceandwhat IwouldhopeisthatiftherewerepeopleherelisteningwhowanttolearnI'mmorethanhappytoeducateandsharethatknowledgebecauseit'sjustforthebettergoodofeverysocietytohavethisasatoolinthetoolboxsoyouhavevideosonyoutubeIhaveabookcalledcannabismythefirstbookIwrotewascannabisrevealedit'sbeentakenoffandreworkedascannabisismedicinethescienceisthescienceinthebookIdon'texpoundonthatbutwehadcannabisismedicinethat'soneofyourbooksthat'smybookyeahandthenIhavesomepublishedresearchonepilepsysoIpublishedsomeresearchin2017withapediatricneurologistatamajorchildren'shospitalinthepacificnorthwestSeattlealongwithanothercannabisclinicianinMaineandwepooledallourpatientsandwefound86%hadareductioninseizuresImeannownoteverybodyhadseizurefreedombut86%ofpatientsyouhavetoremembersomethingtoowhichIleftoutinepilepsywehavealotofmedicinesforepilepsyinourformularyoneinthreepatientsdonotrespondthereisa30%unresponsiveratetoseizuremedicationdowejustletthosepeoplelivewithseizuresandrememberinchildrenit'sdevastatingdevelopmentyesrightifyou'realreadydevelopedas anadultandyoudevelopaseizuredisorderthenitjustmessesupyourlifeyoucan'tdriveandyouworryaboutwhereyou'regoingandthemedicationsareprettydifficultmymotherwasanepileptichaveyouusedketogenicdietyeahusuallyyepketogenicdietnowI'mnotaneurologistsoIdon'ttaketheroleastheneurologistusuallytheneurologistwilldiscusstheketogenicbutifapatientcomestomeandwereusingcannabisIwillsometimesrecommendtheketogenicdiettobehonestcannabisoftenislastresortforthesefamiliessothey'vealreadytriedeverythingincludingketogenicsomeareonsomearenotandIjustwanttosayhowcanitbelastresortImeanjustweknowthatafterthefirsttwoappropriatechosenseizuremedicationsthechanceofrespondingislessthan4%whyarewegoingI'vegotkidsthatcometomethey'vetrialed12differentdrugsIdon'tgetittellusagainhowmuchresponsivenessyougetfromthecannabissoweseesomewherebetween10and15%seizurefreedomsokidswhoarealreadyconsideredwhatwecallrefractoryuntreatablewe'renevergoingtogetcontrolofseizures10to15%ofthosekidsgetseizurefreedomIcan'ttellwhichones86%getatleasta25%reductionsoifyourchildhasfourseizuresaweekyou'redowntothreeseizuresaweekit'sstillbetterthanfourIwouldlovetoseeandnowwehavesomeothercannabinoidson themarketlikethere'sonecalledCBDVcannabinoidthatI'vebeenusingthathasaverynicerateofreducingseizuresespeciallywhencombinedwithCBDagainthesynergyrightandthere'snostudyonthatallIcantellyouisifIhaveafamilyinfrontofmewho'sreportingalloftheseseizuresandIknowthatthiscompoundissafeandit'sundermysupervisionItakeresponsibilityforthatcompoundandthatchildandIholdthatpatient'shandthatparent'shandthroughthatthey'lltell meif itworksor notIteachthemwehaveaprimarycareyou'rekindofinandoutIcallitdrivebymedicineweretheyheredidIseethemandI'mleavingwiththeprescriptionbutwouldyousaybecauseImeanthosechemicalsthat wereallyproducein ourownbodiesImeantheproductiondecreaseswithageohyessowehave, there'sno studiesin humansbut wehavestudiesinanimalsthatshowthatasyouageyourbrainstrengthsbutalsoyourendocannabinoidsystemdoesnotworkaswellandthat'swhyolderpeopleseemlikethey'resayingnowseniorsarethelargestgroupgrowingpopulationusingcannabiswellyeahImeanandthenthere'ssomethingcalledyou maynothaveheardofthiscalledthebeerscriteriaBEERScriteriait'sbasicallylistofmedicationsthatonceyou'reinyoursenioryearshaveactuallymoresideeffectsthanreallybenefitsforalotofpeopleandyou'renotreallysupposedtoprescribethosemedicationsforolderpeopleorifyoudoverycautiouslythey'regettinghandedoutlikecandyIdon'twantmyIhaveafriendwho'stakingcareofherfatherwithdementiaandtheywentintothehospitalandtheywantedtoputhimonadrugthatactuallyhasasideeffectofdeathinseniorsandshecalledmeandshesaidtheywanttoputhimonthisIsaidifyou'reaskingmewhattodowhatIwouldsayisIwouldneverletmyfathertakethatmedicinethat'swhatyouaskadoctorwhatwouldyouwantforyourfamilymemberIthinkit'scrazyactuallythatthey'reallowingdrugsthathavedeathasasideeffectshesaidIdidn'tknowthatIsaidlookitupandshecalledmeandshesaidyou'rerightithasdeathindementiaespeciallybutwhataboutCPTanddementiaandParkinson'ssothat'sagreatquestionwhatwehaveisalotofsmallstudiesandwhenyouaddthemtogetherthedataisverycompellingthatrememberwhatdo weseeindementiaweseeamajorimbalanceinneurochemistryandwhatdocannabinoidsdotoneurochemistryhomeostasisbalanceitoutsoI'vehadthepleasureoftakingcareofmanyofmyparentsbestfriendshereandtherewhohavedementiatheycometomeatdifferentstatessomedownthefardownthelineofdementiasomeearlyonI'llsharewithyouaquickstoryofafriendofminewhosefatherhaddementiawhoItookhimonasapatientshe'sanursesoonceIeducatedherandIlethergoshewouldcheckinwithmewiththeseshewouldsendmevideosofherfathersohewasshutdownstoppedtalkingstoppedeatingforthemostparthereandtheresolosingweightbigtallmanwhowasahighschoolprincipalcoachinthehighschoolwelllovedbythecommunityinvolvedinhiscommunityoneofthoselovelymenwhojustcontributeandispartofeverythinginhiscommunityincludinghisownchildren'sliveshehadthreedaughtersandtheyweretryingtokeephimathomeandhewasbecomingaggressivehewasthrowingthingstheygavehimamagazinehewouldripthemagazineupreallystrangebehaviorsstoppedsleepingatnighttheyweretakingturnswithbeingupwithhimwhenhewasupandkindofthenextstepwastomovehimoutofthehomeintoafacilityandtheyreallywantedtokeephimathomeandsosheaskedmeaboutcannabisandIsaidsurelet'stryitIhavevideosofhimstandingatthestovebeingsupervisedcookingdinnerafterhestartedcannabismedicineIhaveavideoofhimwheresomebodybroughthimapieallofhisfriendswouldcomeandvisithimhereandtherehehadapiesittinginfrontofhimandthedaughtersayswhobroughtyouthatpieyoucouldseehe'sthinkingandhesaystherightnameandshesaysyou'rerightyougotitrightdaddoyouwanttocutthepieandhepullsthedrawertolookfortheproperutensiltocutthepieandhepullssomethingoutthat'snotforthepiecan'trememberwhat itwasspatulaorsomethingandhelooksatitandhesaysthat'snottherightthingandheputsitbackinthedrawerandtakesoutthepiesliceorwhateversoshesaysheneverwouldhavedonethatbeforethefactthatwehadaconversationthefactthathecouldtellthedifferencebetweenthisutensilandthisutensilIhaveavideoofhimdancingwithhisdaughterinthelivingroomIhaveavideoofhimeatinghisfoodthathemadehebecameengagedagainnoweventuallyhehadlouisbodydementiaheeventuallypassedawaywellwealldoofhishomeandnotbeaggressiveandnotcausecaregiverburdenandjustthewholethingforeverybodywasbetterrightandtheywhenyouseethatyousayeverybodydeservesthatatleastatrialitmaynotworkineverybodybuttheresearchrightnowatleasttomakeupyourownmindsuresureaveryrecentlypublishedtrialcalledthelibbytrialyoucanlookituplibbynamedafterawomannamedlibbyhersonisaibelieveaclinicianaphysicianunitedstatestheydidsomeresearchona50to1ratiocbdoil50partcbdto1partthcyouarenotgoingtobehighonthisokayandtheystartedthemandtheytitratedthemupover12weeksat2weekmarktheysawincredibleimprovementbythe12weekmarkso3months87%ofthefamilieswhogotcbdreportedbenefits20%ofthefamilieswhogotplaceboreportedbenefitsareyoulookingatit87.2%wellirounddownbutthisisamazingandsothisisaplacebocontrolledtriali'mnotmakingitupiseverybodygoingtorespondnoandisosadyouknowtheotherdayihadaconversationwithafamilytheyhaveasonwho'snow1516hehastwosyndromesbothofwhichareassociatedwithbehavioralchallengeswheniaskedthemomhihowareyoui'mjustcheckingintoseeshesayswellyouknowhowitisit'shardherchildisnotreallyaresponderandi'vetoldherthisshesaidyeahbutwe'restillgoingtokeepitasabackupmedicinebecausewhenweneedhimtobecalmitwillmakehimcalmenoughthatatleasthe'snotliketheyhavebeendisinvitedfromfamilyeventsbecausehe'ssodisruptivehedoesn'tthat'sjustwhathisbrainistellinghimhe'snotdoingitonpurposethisiswhathisbrainistellinghimtodobutshesaidifwegivehimthisbeforewegoshesaidhedoesn'tcausehesitsalittletoostilllikehe'snotthebestresponderwe'renotgettingthegreatestresponsefromhimbutitdoesraininitenoughsotheycanatleastparticipateintheirlifesothere'sandItalkaboutthisinmytalktomorrowtherearereallygreatresponderstherearepartialrespondersandthenthere'sasmallpercentageinmyIwouldsayinmyexperiencesomewhere15to20percentofpeopleforwhateverreasonmaybeit'snotgoingtoworkgreatandIasadoctorwhotrialslikeifthisdoesn'tworkforyouwe'llmovetothisifthisdoesn'tworkwe'lltrythisthere'ssomanydifferentcannabinoidsthere'sdifferentformulationsmaybeagummyinsteadofoilrightIdon'tgiveupbutatsomepointwhenIfeelthatyouwanttokeepitinthetoolboxforyourchildoryourfamilymemberdotheynotabsorbitdotheyabsorbitandthentheirbodymetabolizesitbreaksitdownandgetsitoutoftheirsystemsotheydon'tevengetaneffectIhavemetpeoplewhosayItake200milligramsofCBDthatshoulddosomethingtoyouandtheysayIdon'tevenneeditorIdon'tknowbecausethisishomeostasisthingyeahtherearepeoplewhodon'tneeditandifyoudon'tneeditdon'tuseitthere'snoreasonyouknowoneoftheveryinterestingthingsthatwedidn'ttalkaboutisrawcannabiswhenyoutakeitfromtheplanttherawcompoundsweusedtosaythattheyneededtobeheatedupthat'swhypeopledon'tfeelhighfromitdoesn'tmeanthatthey'renotbiologicallyactivepotentpotentantiinflammatoriessoI'mgoing tosharesomethingverypersonaltherawplantincredibleantiinflammatorypropertiessowhatdopeoplejusteattheleavesorwhatthey'lldoistakeitandmixitwithanoillikecoconutoilandputitinacapsuleandtakeitsoI'mgoing tosharetwoquickstoriesifthat'sokaybecauseIknowIhaveayoungmanthatcametoseemebodybuilderbigguycameinandheshowsmehisletterbecauseyouhavetoprovetometoapproveyousoyoucan'tcomeinandsayIhaveanxietysotheycomefromotherdoctorstomerightandthey'realreadydiagnosednowsometimesthediagnosisiswrongbutmostofthetimeit'srightandhesaidtomeItoremybicepmuscledoingsomekindofworkoutsomethingorotherandhesaidthecannabisreallyhelpsmeI'mverycarefulaboutwhatIeatpillstheygavemeopioidstheygavemeantiinflammatoryhesaidbutwhenIusetheplantmypaingoesawayandinflammationgoesawayIsaidhowdoyoutakeithesaidIeatitIsaidlikeingummiesorbrowniehesaidnoIjusteattheplantandIkindofIhadneverheardthatbeforeandthisisearlyoninmycareerandIkindoflookedathimlikehmmheeats therawplantwehaven'tcomeacrossthatbeforeandIsaidit'smyunderstandingyouhavetoheatitforittobebiologicallyactivehegoesI'mtellingyouitworkssoIlearnedsomethingthatdayrightokaysothen Istartlookingintotherawit'snotmuchinformationbutthere'ssomemaybesomeantiinflammatorymechanismsinthereandnowsomemorerecentresearchhasshownthattherearesomepotentantiinflammatoryeffectsespeciallyCBDAmyhusbanddrivesfastcarsforalivingokayheworksfordrivingPorschesdon'tfeelsorryforhimhewoulddoitforfreeheprobablypaidtodoitokayhecannotusecannabisbecauseifhedrugtestpositiveforTHChewilllosehisjobweneedhimtohavethatjobfouryearsagoasanavidhewasverybrieflyaprofessionalsoccerplayeras ayoungmanavidtennisplayermountainbikingjustyouknowavidathletefouryearsagohehadtenyearsagohehadkneesurgerygotafewyearsoutofitbutthenfouryearsagowastoldheneedsafullkneereplacementhecouldn'twalkupanddownthestairsinourhouseourmailboxisoutsideinourneighborhoodhecouldn'twalktothemailboxwedidsomeinterventionwiththeorthopedicsurgeondidn'thelpthistimeandthatdaywecamehomewhenhefoundoutheneededakneereplacementIsaidnowyou'regoingtotakemymedicineandIgavehimCBDAwithnoTHCinitCBDAisrawplantifyoudon'theatitit'snotgoingtohaveTHCplushe'snotusingTHCdominantcannabiswithinfourhourstwohourscomesovertomehesaysIdidnotrealizehowmuchpainIwasinuntilit'sgoneIsaidIhavebeenlivingwithyouforthelastsixweeksyouhavebeenmiserablethewifealwaysknowsthehusbandalwaysknowsyouknowfouryearsnownokneereplacementplayingtennismountainbikingwegaveupthesoccerbecausewedon'twantthekneefullydestroyedbutthat'sokayhehascometolivewithitifhecanstillparticipateintheothersportseverydaymorningandeveningnoimpairedwehavecapsulesthat are15milligramcapsuleseachhetakestwointhemorningandtwobeforehegoestobedandthenheputsonthetopicalrubincannabisonhiskneeonceortwiceadaysowebuyitfromacompanywhodoesitsotheybasicallymashupthecannabisnottheleaftheflowerfromaplantthatwouldmakeCBDisCBDarichokaybecausethat'sit'sgeneticsandIbelievetheyyouknowbasicallymaceratetheplantmaterialkeepitcoldandmixitwithacoconutoilandputitintocapsule15milligramseachagainandifhehasadaywherehe'ssuperactivehe'lltakeextraandthat'sthebeautyofitisthatyoucandialupordialdownhe'lltellyouifhegoesthreeorfourdayswithoutithecanfeelthepainsignalingandtheinflammationdialingitdownsohecanlivehislifewithoutpaineventuallythemanwillneedakneereplacementbutwe'reputtingitoffuntilhe'soutofhisyouknowalittlebitolderbecausehewantstokeepactivemoreactivenowwowgreatstoryit'sbeenincrediblyfascinatingtolistentoyouandIthinkyou'vegivenusa lottothinkaboutprobablyourlistenersaswellsoIjustwanttothankyouforyourimportantworkandforsharingitwithusandIthinkit'sreallyimportanttodoconferenceslikethisonesoyoucanreachmoreearsandspreadthewordandIthinkalsoforthepeopleworkinginthistomeetyouknowtoexchangewhat'shappeningandbutlikenowhereinIcelandwhatwouldyousaytoourparliamentariansImeanwehaveevenbeenthinkingaboutdotheyneedtoacceptthisImeaninparliamentorisitenoughthatbecauseIthinkit'sallowedinEuropetouseitasamedicinesoImeanwearepartofthatmarketthere'smedicalcannabisintheUKthere'smedicalcannabisinGermanyandsomeotherplacesaswellIknowFranceisstartingtolookatitaswellPortugalbutdotheyneedtoallowitlikeonparliamentordotheyjustImeanbecausewhenanewdrugcomesinforexamplewhentheopioidscameintheparliamentdidn'tsayokayitwasjusttheinstitutethatsaysyesornoIthinkaboutnewmedicinethat'scominginsotherewasadiscussionamongsomeofusspeakersattheconferencethismorningaboutwheredoespoliticsplayaroleincannabismedicineandifyouaskmeitdoesn'tpoliticsshouldnotbeinvolvedbutwearestuckwiththelandscapethatwehavewhichisthatcannabishasbeenmadeillegalandsobeforethey'regoingtosaylet'smakeitlegalthey'regoingtoneedsomemoreinformationandsoIalwaysputmyselfoutthereandsayifyouneedmetospeaktosomebodyabouttheendocannabinoidsystemandthesciencestoprelyingonpropagandaandononeperson'sstoryabouthowcannabisdestroyedtheirchild'slifewellIhaveathousandmanythousandsofstorieswherecannabissavedtheirchild'slifesowehavetoit'snuancedit'snotyesornoit'snotitworksoritdoesn'tworkit'snuancedhowareyouusingitwhatproductsareyouusingwhatisthesciencebehinditandtomethescienceisirrefutableifyouneedmoreprooftalktothepatientswhosefamiliesarestrugglingwhonowarenotstrugglinganymorethat'sityouhavetoeducateyourselfwecannotliveinthepropagandaworldanymoreitjustisnotthewaytoliveit'snotthewaytobekindandcompassionatetoourpopulationofpeoplewhoneedhelpIthinkthosearejustgreatfinalwordshereBonniethankyousomuchforbeingwithushereandgoodluckwitheverythingandIhopereallythatwehavecourageouspoliticianstochangetherulesandthelawsaboutthissoallthepeoplethatneedthisandarenotgettingitcanhaveaccessthat'sallitisjustaccessyoudon'thavetotakeitifyoudon'twantit'saccessforthosepeoplewhoneeditthankyouopenyourearsandlistentotheevidencenotthepropagandayeahthankyoucomeagainpleasethankyou
